1Fire A,Xu S,Montgomery M K,et al.Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans[J].Nature,1998,391:806-811.
3Vayssie L,Vargas M,Weber C,et al.Double-stranded RNA mediates homology-dependent gene silencing of gamma-tubulin in the human parasite Entamoeba histolytica[J].Mol Biochem Parasitol,2004,138 (1):21-28.
4Best A,Handoko L,Schluter E,et al.In vitro synthesized siRNAs elicit RNA interference in African trypanosomes an in vitro and in vivo analysis[J].J Biol Chem,2005,280(21):20573-20579.
5Durand-Dubief M,Bastin P.TbAGO1,an Argonaute protein required for RNA interference,is involved in mitosis and chromosome segregation in Trypanosoma brucei[J].BMC Biol,2003,1(1):2.
6Mohmmed A,Dasaradhi PV,Bhatnagar RK,et al.In vivo gene silencing in Plasmodium berghei-a mouse malaria model[J].Biochem Biophys Res Commun,2003,309(3):506-511.
7Nelson M R,Marnellos G,Karnmerer S,et al.Large-scale validation of single nucleotide polymorphisms in gene regions[J].Genome Res,2004,14:1664-1668.
8Huynh TT,Huynh VT,Harmon MA,et al.Gene knockdown of gamma-glutamylcysteine synthetase by RNAi in the parasitic protozoa Trypanosoma brucei demonstrates that it is an essential enzyme[J].J Biol Chem,2003,278(41):39794-39800.
9Wilkinson SR,Horn D,Prathalingam SR,et al.RNA interference identifies two hydroperoxide metabolizing enzymes that are essential to the bloodstream form of the african trypanosome[J].J Biol Chem,2003,278(34):31640-31646.
10Comini MA,Guerrero SA,Haile S,et al.Valdiation of Trypanosoma brucei trypanothione synthetase as drug target[J].Free Radic Biol Med,2004,36(10):1289-1302.
4[9]Ji M-J, Su C, Wu H-W , et al.Gene Expression Profile of CD4 + T Cell Rev eals an Interferon Signaling Suppression Associated with Progression of Experimental Schistosoma japonicum Infection. Cellilar Immunology, 2003, 224:55~62
5[10]Shen L, Zhang Z-S, Wu H-W, et al.Down-Regulation of Specific Anti gen-Driven Cytokines Production in a Population with Endemic Schistosoma japonicum Inf ection. Clin Exp Immunol, 2002, 129:339~345
6[11]Schreiber G. The Evolutionary and Integrative Roles of Transthyretin in Th yroid Hormone Homeostasis. J Endocrinol, 2002,175(1):61~73
7[12]Hu W, Yan Q, Shen D-K, et al. Evolutionary and Biomedical Implications o f a Schistosoma japonicum Complementary DNA Resource. Nature Genetics,2003, 35: 139~147
8[13]Reddan J R, Wilson-Dziedzic D. Insulin Growth Factor and Epidermal Growth Fact or Trigger Mitosis in Lenses Cultured in a Serum-Free Medium. Invest Ophthalmol Vis Sci,1983, 24(4):409~416
9[14]Liou J C, Tsai F Z, Ho S Y. Potentiation of Quantal Secretion by Insulin- Like Gr owth Factor-1 at Developing Motoneurons in Xenopus Cell Culture. J Physiol, 2003,553(3):719~728
1Jorgensen R.Altered gene expression in plants due to trans in- teractions between homologous genes[J].Trends Biotechnol,1990,8(12):340-344.
2Cogoni C,Romano N,Macino G.Suppression of gene expression by homologous transgenes[J].Antonie Van Leeuwenhoek,1994,65(3):205-209.
3Guo S,Kemphues KJ.par-1,a gene required for establishing po- larity in C.elegans embryos,encodes a putative Ser/Thr kinase that is asymmetrically distributed[J].Cell,1995,81(4):611-620.
4Fire A,Xu S,Montgomery MK,et aL Potent and specific ge- netic interference by double-stranded RNA in Caenorhabditis ele- gans[J].Nature,1998,391(6669):806-811.
5Ullu E,Tschudi C,Chakraborty T.RNA interference in proto- zoan parasites[J].Cell Microbiol,2004,6(6):509-519.
6Correnti JM,Brindley PJ,Pearce EJ.Long-term suppression of cathepsin B levels by RNA interference retards schistosome growth[J].Mol Biochem Parasitol,2005,143(2):209-215.
7Mcgonigle L,Mousley A,Marks NJ,et al.The silencing of cysteine proteases in Fasciola hepatic a newly excysted juveniles using RNA interference reduces gut penetration[J].Int J Para- sitol,2008,38(2):149-155.
8Kennerdell JR,Carthew RW.Use of dsRNA-mediated genetic inter- ference to demonstrate that frizzled and frizzled 2 act in the wing- less pathway[J].Cell,1998,95(7):1017-1026.
9Nakano H,Amemiya S,Shiokawa K,et al.RNA interference for the organizer-specific gene Xlim-I in Xenopus embryos[J].Biochem Biophys Res Commun,2000,274(2):434-439.
10McCaffrey AP,Meuse L,Phan TT,et al.Gene expression:RNA interference in adult mice[J].Nature,2002,418(6893):38-39.