双黄连注射液治疗母畜子宫内膜炎的临床试验

Clinical Test of Shuanghuanglian Injection on Female Animal's Endometritis

临床选取自然发生子宫内膜炎的猪只236头,羊241只,牛180头。将发病母畜随机分为高、中、低剂量组,药物对照组和阳性对照组,分别采用肌肉注射和子宫灌注两种给药途径交替给药,一日一次,连续3次给药后,停药观察7 d。结果双黄连注射液高剂量组与中剂量组对子宫内膜炎的疗效优于化学药物对照组,差异均显著(P<0.05);低剂量组治疗效果与化学药物组差异不显著(P>0.05)。双黄连注射液对家畜无毒副作用,而且还能增强家畜的抵抗力,因此可作为治疗母畜子宫内膜炎的首选药物。

236 pigs, 241 goats and 180 cows that infected endometritis naturally on clinic were divided randomly into 5 trial groups which are high dose group, middle dose group, low dose group, compared drug group and masculine control group. By ways of intramuscular injection and affusing drugs into uterus alternately as route of administration, one time a day for three days and observed seven days later after quit drugs. As a result, the high and middle dose groups of Shuanghuanglian injection were preceding to chemical drugs group on treating female animals＇ endometritis, and the difference was significant （ P 〈 0.05 ）. There was no obvious difference between low trial group and chemical drugs group （ P 〉 0.05 ）. As Shuanghuanglian preparation and has no side and toxin-effects, maybe it can be the first choice on clinic.