纵隔淋巴瘤26例临床分析

CLINICAL ANALYSIS OF TWENTY-SIX CASES WITH MEDIASTINAL LYMPHOMA

本文介绍26例纵隔淋巴瘤。20例获得病理诊断,何杰金氏病4例,非何杰金氏病16例。临床表现有三大症侯群:全身症状:发热、多汗、食欲下降、消瘦和乏力等;纵隔肿大淋巴结压迫或侵犯胸内组织引起的局部症状:咳嗽、胸闷、气急和胸痛等;及远处转移引起的相应症状。确诊方法:浅表淋巴结活检13例,占病理阳性的65％,此外有骨髓穿刺、胸水检查、胸膜活检、胸内肿块穿刺、扁桃体切除及脾切除等。最后讨论了纵隔淋巴瘤的诊断及白血病化问题。

This article reports 26 cases of mediastinal lymphoma. Among them were 17 males and 9 females, and the average age was 31.2 years. Pathologic diagnosis was established in 20 cases, 4 of which were Hodgkin's disease and 16 non-Hodgkin's. Clinical manifestaions were divided into 3 groups: systemic symptoms such as fever, sweating, anorexia, loss of weight and fatigue; local symptoms due to enlarged mediastinal lymph nodes such as cough, tachypnea, chest pain and others; and associated manifestations owing to distant metastasis. The diagnostic procedures consisted of superficial lymph node biopsy in 13 cases, accounting for 65% of positive results, aspiration biopsy ofbone marrow, pleura and intrathoracic mass, biopsy of specimens of tonsillectomy and splenectomy and examination of exfoliative cells of pleural fluid. Diagnosis of mediastinal lymphoma and lymphcytic leukemia is also discussed .