基因修饰树突状细胞诱导抗血液肿瘤效应的研究进展
被引量:1
摘要
白血病/淋巴瘤等血液肿瘤经联合化疗,可以获得完全缓解,但难彻底消灭肿瘤微小残留病(MRD)。基因修饰的树突状细胞瘤苗以其增强肿瘤细胞的免疫原性,启动机体的特异性抗肿瘤免疫应答,成为清除MRD的一种有希望的途径。本文就树突状细胞的生物学特性及其诱导培养,基因转移载体的选择,以及不同来源基因修饰DC诱导抗血液肿瘤的特点等方面的研究进展进行综述。
出处
《国际输血及血液学杂志》
CAS
2006年第2期163-166,共4页
International Journal of Blood Transfusion and Hematology
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