胃黏膜癌前病变大鼠舌诊特点的研究

Study on glossoscopy characteristic of gastric mucosal precancerous lesions rat

目的观察胃黏膜癌前病变大鼠的舌诊特点。方法以Wistar大鼠造成胃黏膜癌前病变模型,从舌象肉眼观察、数码相机摄取舌像计算机客观化分析、舌面pH值检测、舌病理及舌苔脱落细胞观察等多方面进行研究。结果对照组大鼠以淡紫舌为主,而造模组大鼠多呈紫暗舌或有瘀斑;舌像摄影计算机客观化分析2组比较有显著性差异;造模组舌面pH值较对照组升高,有统计学意义;舌病理检查造模组有毛细血管扩张瘀血及细胞空泡变性等改变。结论胃黏膜癌前病变大鼠的舌诊具有一定的特征性,提示了癌前病变瘀血机制的存在。

Objective It is to observe the glossoscopy characteristic of gastric mucosal precancerous lesions rat. Methods Gastric mucosal precancerous lesions model was made with Wistar rat. The tongue nature, computer externalization analysis of tongue image, pH of tongue surface, tongue pathology and exfoliative cell of tongue coating were studied. Results The tongue nature of control group mainly showed light purple, but that of model group mainly showed dark purple or with ecchymosis, there is significant difference in the two groups. The pH of tongue surface of model group was obviously higher than that of control group. The tongue pathology of model group was also very different from that of control group, Conclusion The glossoscopy of gastric mucosal precancerous lesions rat has definite characteristic and it indicates the stagnated blood mechanism of precancerous lesions.