吸烟人群血清癌胚抗原检测结果分析

Analysis of results in detection of serum carcino-embryonic antigen in smokers

目的了解吸烟人群中血清癌胚抗原(Carcinoembbryonic antigen简称CEA)含量变化并与非吸烟组进行比较,提示人们吸烟危害性。方法采用化学发光免疫分析法测定非吸烟组1200例,吸烟组共1107例,又把吸烟组分成3组,并把它们进行比较。结果吸烟10年以下CEA含量<5μg/L范围占百分比与正常对照组比较差异没有显著性(P>0．05),而吸烟10～20年和20年以上两组的CEA含量与正常对照组比较差异有显著性(P<0．01)。结论吸烟时间越长。血清CEA含量增高可能性越大,而CEA增高又与肺癌有关,所以吸烟引起肺癌可能性比非吸烟人群机会增大。

Objective To understand the variation of content of the serum earcinoembbryonic antigen （CEA） in the smokers. Methods 1 107 smokers were divided into three groups according to the number of smoking years . Serum CEA in smoking group and in nonsmoking group were detected with Mieropartical Enzyme Immunoassay （MEIA） technology respectively. Results The level of the serum CEA increased obviously in the groups with smoking duration of over 10 years （P 〈 0.01）, hut not in the group with a smoking duration of less than 10 years （ P 〉 0.05）. Conclusion There is the possibility that the level of serum CEA will increases higher along with the increase of number of smoking years. Thus the possibility of acquiring lung cancer in smokers is increased as the increase of CEA is associated with lung cancer.