延边农村地区汉族和朝鲜族居民血脂异常分布特征比较

Comparison of distributive characteristics of abnormal blood lipid between the Han and Korean-Chinese nationalities in the urban of Yanbian area

目的:调查分析延边农村地区汉族和朝鲜族居民血脂异常分布特征。方法:调查于2004-08/09完成,随机抽取延边地区汪清县大兴沟镇汉族和朝鲜族居民455名,均自愿参加调查。排除混血民族。①按统一的调查表(包括研究对象的一般情况、心脑血管疾病的既往史及家族史等)进行家访询问调查。②测量身高、体质量、腰围、臀围、血压等。取清晨空腹静脉血,测量血清总胆固醇、三酰甘油、高密度脂蛋白胆固醇、空腹血糖等指标,均用全自动生化分析仪测定。③分析血脂异常与其影响因素的关系采用Logistic回归分析。结果:调查问卷、体格检查及生化指标检测结果完整者455人。①两民族血脂异常率比较:朝鲜族男女血脂异常率显著高于汉族眼84.1%,88.8%;30.7%,42.1%(χ2=48.9,53.4,P<0.01)演,而且其高胆固醇血症、低高密度脂蛋白胆固醇血症、单纯高收缩压、单纯高舒张压、高血糖等患病率也均高于汉族(P<0.05～0.01),朝鲜族女性的高三酰甘油血症患病率高于汉族女性(P<0.01)。②血脂异常者不同血脂类型构成:延边农村地区的血脂异常以低高密度脂蛋白胆固醇为主要类型。③血脂异常相关因素的多因素分析:最终进入方程的因素分别为:民族、性别、收缩压、空腹血糖及腰围(OR=0.108,95%CI押0.061～0.190鸦OR=1.539,95%CI押0.970～2.441鸦OR=1.670,95%CI押1.020～2.757鸦OR=2.565,95%CI押1.270～5.183鸦OR=1.890,95%CI押1.196～3.008)。结论:延边农村地区汉族和朝鲜族人群血脂异常患病率存在差异,该地区的血脂异常与居民的民族、性别、收缩压、空腹血糖及腰围有关,并且以低高密度脂蛋白胆固醇血症为主要类型。

AIM： To investigate the distribution character of abnormal blood lipid in Han and Korean nationalities in urban of Yanbian area. METHODS： The investigation was performed from August to September 2004. Using simple randomized principle, 455 people of Han nationality and Korean-Chinese in the Daxinggou town, Wangqing county of Yanbian area were selected. They all agreed to join the survey voluntarily. Halfblood members were excluded. ①According to the unified questionnaire （contained general condition of testees, past history and family history of cardiovascular disease） home visit was done. ②Height, body mass, waistline, breechline and blood pressure, etc. were measured. Fasting abdominal vein was got. Serum total cholesterol, triacylglycerol, HDL cholesterol, fasting glucose, etc. were detected with full-auto biochemical analyzer. ③Abnormal blood lipid and its related factors were analyzed with Logistic regression analysis. RESULTS： Totally 455 persons were with complete questionnaire, physical examination and biochemical index.①Comparison of abnormal rate of blood lipid of the two nations： The abnormal rate of blood lipid in males and females of Korean nation was higher significantly than that in the Han nation [84.1% ,88.8% ;30.7% ,42.1%（x^2=48.9,53.4,P 〈 0.01）]. The prevalence rates of hypercholesterolemia, low and high density lipoprotein cholesterol, single high systolic pressure, single high diastolic pressure, high glucose, etc. were higher than those of Han nation （P 〈 0.05-0.01 ）. The prevalence rate of triacylglycerol symptom in female of Korean was higher than that of Han nation （P 〈 0.01）. ②Construction of different blood lipid type in abnormal blood lipid patients： Low and high density lipoprotein cholesterolemia was mainly in countryside of Yanbian area. ③ Multiple analysis of related abnormal blood lipid： Finally, the factors entered equation were nation, sex, systolic pressure, fasting glucose and waistline （OR=0.108, 95%CI：0.061-0.190; OR=1.539, 95%CI：0.970-2.441; OR= 1.670, 95%CI：1.020-2.757; OR=2.565, 95%CI：1.270-5.183; OR= 1.890, 95%CI： 1.196-3.008）. CONCLUSION： The distribution of the prevalence rate of abnormal blood lipid among Han and Korean nationalities in urban of Yanbian area are significant difference, and the abnormal blood lipid is related with nation, sex, systolic blood pressure, fasting blood-glucose, waistline, which mainly is low high density lipoprotein-cholesterolemia.