小儿脑性瘫痪早期诊断中的相关辅助检查

Associated auxillary examinations in the early diagnosis of cerebral palsy in children

目的:综合分析小儿脑性瘫痪早期诊断中的相关辅助检查手段及其临床作用。资料来源:应用计算机检索湖南省儿童医院网上办公系统-应用系统-医院知识仓库(CHKD期刊全文库)1994-01/2005-01有关小儿脑性瘫痪早期诊断相关辅助检查的文献,限定语言种类为中文,以“脑性瘫痪”为检索词进行第一次检索,并在此基础上分别以“头颅电子计算机断层扫描、磁共振、单光子发射电子计算机断层扫描、经颅磁刺激运动诱发电位、脑电图、头颅超声、脑干听觉诱发电位、眼视光学、染色体、TORCH”等为检索词进行第二次检索。资料选择:通过对文献的回顾性分析,选择与脑性瘫痪早期诊断相关的辅助检查文献。排除重复及综述类文献。资料提炼:第一次检索共有865篇文献。第二次检索文献内容分别如下:头颅电子计算机断层扫描41篇、磁共振13篇、单光子发射电子计算机断层扫描2篇、脑电图15篇、脑干听觉诱发电位12篇、经颅磁刺激运动诱发电位1篇、头颅超声3篇、眼视光学2篇、TORCH2篇及染色体1篇,对这些文献进行分类整理。资料综合:在小儿脑性瘫痪早期诊断中临床常用的检查手段有头颅电子计算机断层扫描、磁共振、单光子发射电子计算机断层扫描、经颅磁刺激运动诱发电位、脑电图、头颅超声、脑干听觉诱发电位、眼视光学、染色体、TORCH等。通过这些检查可以了解脑性瘫痪患儿的形态学改变和功能学改变,也可了解相关致病因素和发病途径,为脑性瘫痪的早期诊断提供重要线索和依据。结论:将上述检查手段与临床实践有机结合,可明显提高脑性瘫痪早期诊断水平,对于观察疗效、判断预后及指导康复治疗有重要价值。

OBJECTIVE： To analyze synthetically related assisted examination ways and its clinical application in the early diagnosis of cerebral palsy （CP） in Children. DATA SOURCES： With the help of computer, entering into the office system of Hunan Provincial Children＇s Hospital-application system-China Hospital Knowledge Database （CHKD）, retrieving the related literatures about assisted examination of early diagnosis of cerebral palsy of children from January 1994 to January 2005 in Chinese with the key word of ＂cerebral palsy＂ in the first search, and with the key words of ＂computer tomography （CT）, magnetic resonance （MRI）, single photon emission computerized tomography （SPECT）, transcranial magnetic stimulation （TMS）, motor evoked potentials （MEP）, electroencepalograph （EEG）, uhrasonography, auditory evoked potential （AEP）, ophtalmology, chromosome, TORCH＂ at the second search. STUDY SELECTION： The literatures related to auxiliary measurements in the early diagnosis of CP were selected. Papers with repetitive research and reviews were excluded. DATA EXTRACTION： There were 865 literatures at the first time, the results at the second time were as follows： 41 literatures on CT, 13 papers on MRI, 2 articles on SPECT, 15 literatures on EEG, 12 on AEP, 1 on TMS-MEP, 3 on uhrasonography, 2 on ophthalmology, 2 on TORCH and 1 on chromosome. These literatures were classified and arranged. DATA SYNTHESIS： The methods used in the early diagnosis of CP were CT, MRI, SPECT, TMS-MEP, EEG, uhrasonography, AEP, ophthalmology, chromosome and TORCH etc., which help to know the anatomical and functional changes of CP, and to catch contributive factors and the pathogenesis, providing with important clues and evidences for the early diagnosis of CP. CONCLUSION： Combined organically these measurements with clinical examination can improve markedly the level of early diagnosis of CP, which have important values on observational curative effect, judging prognosis and instructing rehabilitative treatment.