针刺分离联合结膜下注射5-FU治疗青光眼术后早期滤过泡功能不良

Treating earlier malfunction filtering bleb with acupuncture separation combined with injection of 5-FU around the filtering bleb after glaucoma filtration surgery

目的:探讨对于青光眼术后早期功能不良的滤过泡采用针刺分离联合结膜下注射5-FU的治疗效果。方法:青光眼滤过术后3mo内25眼功能不良的滤过泡采用针刺分离滤过泡周围纤维瘢痕,然后结膜下注射5-FU5～10mg,隔日1次共5次,分析治疗后眼压和滤过泡形态的变化及治疗后的眼部并发症。结果:25眼中,21眼眼压控制在21mmHg以下,其中18眼在15mmHg以下;滤过泡形态:有19眼表现为功能性滤过泡;并发症:常见并发症有角膜上皮损伤、结膜下出血、滤过泡损伤等。结论:对于青光眼术后早期功能不良的滤过泡采用针刺分离联合结膜下注射5-FU是安全、有效的。

AIM： To explore the therapeutic efficacy of treating earlier malfunctional filtering bleb after glaucoma filtration surgery with acupuncture separation combined with injection of 5-FU around the filtering bleb. METHODS： Twenty-five eyes of malfunctional fleering bleb after glaucoma filtration surgery in 3mo were treated with acupuncture separation combined with injection of 5-FU around the filtering bleb every 2d to total 5 times, then to analyse the ocular pressures, the forms of the filtering blebs and the complications. RESULTS： Among the 25 eyes, there were 21 eyes that the ocular pressures were below 21mmHg, 18 eyes below 15mmHg and 19 eyes with the functional filtering bleb.The most common complications were corneal epithelium damaged, subconjunctival hemorrhage and filtering bleb damage, etc. CONCLUSION： It is safe and effective to treat earlier malfunctional filtering blebs after glaucoma filtration surgery with acupuncture separation combined with injection of 5-FU around the filtering bleb.