不同肝功能指标对评估肝动脉化疗栓塞术耐受性的意义

Different importance of each index reflecting liver function in evaluating the tolerance of interventional chemoembolization

目的评价各项肝功能指标对评估肝动脉化疗栓塞术(TACE)耐受性的意义,探寻能更好反映肝脏储备功能及对TACE耐受性的指标。方法按术后出现的肝功能损害程度,将78例接受TACE的原发性肝癌患者分为两组,对两组患者术前的各项肝功能指标进行统计分析。结果两组的血清总胆红素、谷丙转氨酶、谷草转氨酶、白蛋白差异均无统计意义(P>0.05),而血清胆碱脂酶、前白蛋白差异均有统计意义(P<0.01、P<0.05)。结论血清胆碱脂酶及前白蛋白能更客观、灵敏地反映肝脏储备功能,更好地反映患者对TACE的耐受性。

Objective To search for the index which can reflect the reserved function of liver and the tolerance of interventional chemoembolization better. Methods 78 patients with hepatocarcinoma treated by interventional chemoembolization classified by two groups according to the liver function damage after operation. Liver functions among the two groups were analyzed with statistics methods. Results There was no difference in the total bilirubin, alanine aminotransferase, aspartate aminotransferase, albumin of the pro-operation among the two groups （P〉0.05）, but the difference in the serum cholinesterase and prealbumin was obviously （P〈0.01, P〈0.05）. Conelusion Serum cholinesterase and prealbumin were the better indexes in evaluation the liver function and the tolerance of interventional chemoembolization.