血清唾液酸含量在恶性肿瘤诊断中的临床意义

Clinical significance of serum sialic acid in diagnosis of malignant tumor

目的探讨血清唾液酸含量在恶性肿瘤诊断中的临床意义。方法选择三组人群即正常对照组、良性疾病组和恶性肿瘤组,采用单一化学比色法检测血清唾液酸含量。结果恶性肿瘤组血清唾液酸含量明显高于正常对照组和良性疾病组,有高度显著性差异(P<0．0001)。同时,唾液酸含量测定对恶性肿瘤的阳性检出率也较其它两组有显著性意义(P<0．0001)。结论血清唾液酸检测可作为恶性肿瘤的辅助诊断指标。

Objective： To study the dinieal significance of serum sialic acid in the dignosis of malignant tumor. Methods： Content of serum sialicacid in the groups of normal control, benign lesion and malignanttumor was assayedby means of single chemistry chromometry. Results： The results showed that serum sialic acid level was significantly higher in patients with malignant tumor than that in the normal controls and benign lesion group, and there was an obvious difference （P 〈 0.0001）, At the same time, in patients with malignant tumors, sialie acid positive rate was obviously higher than that of the other two groups （ P 〈 0. 0001）. Conclusion： The determination of serum sialic acid may be the accessorial index for the diagnosis of malignant tumors.