王不留行与硬叶女娄菜止痛、消炎效能的比较研究

A Comparative Study on Efficacy of Saponariae Vaccariae Semen and Melandryi Firmi Herba Extracts on Analgesic and Anti-inflammatory

目的:比较验证中国临床所用王不留行与韩国临床所用王不留行即硬叶女娄菜的止痛和消炎功效。方法:取韩国出产的硬叶女娄菜和中国河南出产的王不留行分别煎汤、减压浓缩,灌胃两组Sprague Dawley系大鼠和I.C.R小鼠30min后,用0.7%醋酸腹腔注射及5%醋酸足跖皮下注射,并与生理盐水作对照,测量和观察止痛和消炎效果。结果:王不留行组与硬叶女娄菜组在止痛和消炎功效上较生理盐水组显示显著差异。结论:王不留行与硬叶女娄菜止痛和消炎效能优秀。

Objective： to compare the efficacy of both Saponariae Vaccariae Semen and Melandryi Firmi Herba extract on analgesic effects and anti-inflanmmtory effects. Methods： the writhing syndrome of pain on I. C. R mice induced by 0.7% acetic acid, and inflammatory on Sprague Dawley rats induced by 5 % acetic acid. Saponariae Vaccariae Semen and Melandryi Firmi Herba extract were made into decoction to gavage two groups in comparison with normal saline control group. To observe the effects of analgesic and antiinflammatory. Results： Saponariae Vaccariae Semen and Melandryi Firmi Herba extract groups showed significant difference on analgesic and anti-inflammatory in comparison with control group. Conclusions： Saponariae Vaccariae Semen and Melandryi Firmi Herba extract had good effects of analgesic and anti-inflanmmtory.