急冠平治疗急性冠脉综合征临床研究

A Clinical Study on the Applying of Jiguanping Treating Acute Coronary Syndrome (ACS)

目的:探讨急性冠脉综合征(ACS)临床上应用急冠平中药治疗的有效性及预防并发症的获益程度。方法:将143例ACS患者随机分为两组,中西医结合治疗组(中西医组)72例,西药治疗组(对照组)71例。两组均按ACS/AHA2002年3月17日网上公布的抗缺血、抗凝治疗建议进行,中西医组加用急冠平中药观察抗心绞痛、心律失常、泵衰竭及死亡情况。结果:中西医组心绞痛缓解率91.6%,对照组64.8%;心电图改善情况中西医组87.5%,对照组63.3%,二者均优于对照组(P<0.05);统计心律失常发生率中西医组58.3%,对照组88.7%,有显著差异(P<0.05);泵衰竭与死亡情况中西医组比对照组有显著下降。

Objective： To explore the effect of jiguangping on treating ACS and the effect on preventing complicating disease, Methods： 143 cases of ACS were devided into two groups： 72 cases of western and Chinese medicine treatment group, and 71 cases of western medicine treatment group. Two groups were treated by the standards of antiischemia, anticoagulation of ACS/AHA published on the net in 2002.3.17. Observed the improvement of anginal, arrhythmia, pump failure and death with the treatment of western and Chinese medicine plus jiguanping. Results： in western and Chinese medicine treatment group, 91.6% eases of anginal were improved, and in control group, it was 64.8% ; in western and Chinese medicine treatment group 87.5% cases of electrocardinogram were improved, and in control group, it was 63.3%. The effects of treatment group were better than the control group （P〈 0.05）. 58.3% cases in western and Chinese medicine treatment group caught arrhythmia, and in control group it was 88.7%, and there was markedly difference （P〈 0.05）. Pump failure and death in two groups were markedly lowered.