^(12)C^(6+)离子辐照人胃癌细胞系BGC823的氧效应研究

Oxygen Effect in ^(12)C^(6+) Irradiation of BGC823 Cells

以体外培养的人类胃癌细胞系BGC823为材料,用兰州重离子加速器提供的能量为20MeV/u的12C6+离子,分别在富氧(95%O2+5%CO2)和自然条件下辐照细胞,测得这种离子的氧增比近似为1,说明在中等能量区12C6+离子有很低的氧效应。

Gastric tumour BGC823 cells cultured in natural and rich oxygenic（95 %O2＋5% CO2 ）environment are irradiated with energy of 20 MeV/u ^12C^6＋ ions at HIRFL. Average OER≈1 is deduced from survival curves for cells in natural and rich oxygenic environment. This relatively low OER value indicates that medium energy carbon ions are suitable for the cancerous therapy.