21例肺硬化性血管瘤的诊断与外科治疗分析

Diagnosis and surgical treatment of pulmonary sclerosing hemangioma

目的分析硬化性血管瘤的临床特点、诊断、外科治疗和预后情况,进一步提高对该病的认识。方法回顾分析我院1999-2005年收治的21例肺硬化性血管瘤。结果全组中女性占85.71%(18/21),发病中位年龄40岁;14例(66.67%)无任何症状,放射影像学表现为边缘清晰的圆形或类圆形软组织结节影,19例(91.48%)密度均匀,4例(19.05%)有点状钙化;全部行手术治疗,无并发症和手术死亡;全组术后平均随诊2.7年无转移复发。结论肺硬化性血管瘤术前诊断较困难,确诊依靠病理,手术是肺硬化性血管瘤的有效治疗方法。

Objective To analyze the clinical features, diagnosis, surgical treatment and prognosis of pulmonary sclerosing hemangioma. Methods The clinical data of twenty-one patients with pulmonary sclerosing hemangioma admitted to our hospital from 1999 to 2005 were analyzed retrospectively including clinical and pathological features, image characteristics, operation approach and follow-up. Results Eighteen out of twenty-one （85.71%） patients were female. The average age of the patients was 40, ranged from 15 to 57 years old, and the course of disease was 7 d to 10 months （ averaging 1.5 months）. Fourteen of 21 patients （66. 67% ） had no symptoms. The tumors presented as round or nearly round nodules or mass with clear edge on the radiograph. All patients received operation without complication or mortality. Immunohistochemical findings indicated that the tumor cells were positive for neuroendocrine markers. There was no recurrence or metastasis in the follow-up of 2. 7 years. Conclusion The diagnosis of pulmonary sclerosing hemangioma is very difficult preoperatively, so depends on the examination of pathological sections. The surgical treatment for pulmonary sclerosing hemangioma leads to a good prognosis.