摘要
关于抑制素的研究已经有70余年的历史,随着研究的进一步深入,抑制素在人类辅助生殖技术中的作用越来越受到重视了。然而要达到利用抑制素或基于其结构的复合物制备药物来调节生育力,仍然任重而道远。本文就抑制素的研究基础、生理作用及在人类辅助生殖技术中的应用作一综述。
出处
《生殖与避孕》
CAS
CSCD
北大核心
2006年第3期169-174,共6页
Reproduction and Contraception
参考文献37
-
1Ramaswamy S,Marshall GR,Mcneilly AS,et al.Dynamics of the follicle-stimulating hormone(FSH) inhibin B feedback 1oop and its role in regulating spermatogenesis in the adult male rhesus monkey (Macacamulatta) as revealed by unilateral orchidectomv.Endcrinology,2000,141(1):18-27.
-
2Mccullagh DR.Dual endocrine activity of the testis.Science,1932,76:19-20.
-
3Groome NP,Illingworth P J,OBrien M,et al.Detection of dimeric inhibin thoughout the human menstrual cycle by two-site enzyme immunoassay.Clin Endocrinol,1994,40(6):717-23.
-
4Groome NP,Illingworth P J,OBrien M,et al.Measurement of dimeric inhibin B throughout the human menstrual cycle.Clin Endocrinol Melab,1996,81(4):1401-5.
-
5Billiar RB,lachos NC,Bureh MG,et al.Up regulation of(alpha)-inhibin expression in the fetal ovary of estrogensuppressed baboos is associated with impaired fetal ovarian folliculogenesis.Biol Reprod,2003,68(6):1 989-96.
-
6Imai K,Khandoken MA,Yonai M,et al.Matrix metalloproteinases-2 and-9 activities in bovine follicular inhibin and steroid concentrations.Domest Anim Endocrinol,2003,24(2):171-83.
-
7Safi M,Onagbesan OM,Bruggeman V,et al.Regulation of inhibin alpha-and beta (A) -subunit messenger ribonucleic ackl levels by gonadotropins and IGF-Ⅰ in cultured chicken granulosa cells.Gen Comp Endocrinol,2003,131(2):159-67.
-
8Bili H,Layen J,Lmmd B,et al.Age-related differences in features associated with polycentric ovary syndrome in normogoadotrophicoligo-amenor-rhoeie infertile women of reproductive years.Eur J Endocrinol,2001,145(6):749-55.
-
9Porchet HC,le Cotonnec JY & Loumaye E.Clinical pharmacology of recombinant human follicle -stimulating hormone.Ⅲ.Pharmacokinatic-pharmacodynamic modelling after repeated subcutaneous administration.Fertil Steril,1994,61(4):687-95.
-
10Eldar-Geva T,Robertson DM,Cahir N,et al.Relationship between serum inhibin A and B and ovarian follicle development after a daily fixed dose administration of recombinant follicle-stimulating hormone.J Clin Endocrinol Melab,2000,85(2):607-13.
二级参考文献12
-
1Carlsen E,Giwercman A,Keiding N,et al.Evidence for decreasing quality of semen during past 50 years[J].BMJ,1992,305 (6854):609-613.
-
2Pierik FH,Vreeburg JT,Stijnen T,et al.Serum inhibin B as a marker of spermatogenesis[J].J Clin Endo Metabcrinol,1998,83(9):3110-3114.
-
3Meachem SJ,Nieschlag E,Simoni M.Inhibin B in male reproduction:pathophysiology and clinical relevance[J].Eur J Endocrinol,2001,145(5):561-571.
-
4Andersson AM,Muller J,Skakkebaek NE.Different roles of prepubertal and postpubertal germ cells and Sertoli cells in the regulation of serum inhibin B levels[J].J Clin Endocrinol Metab,1998,83(12):4451-4458.
-
5Petersen PM,Andersson AM,Rorth M,et al.Undetectable inhibin B serum levels in men after testicular irradiation[J].J Clin Endocrinol Metab,1999,84(1):213-215.
-
6von Eckardstein S,Simoni M,Bergmann M,et al.Serum inhibin B in combination with serum follicle-stimulating hormone(FSH) is a more sensitive marker than serum FSH alone for impaired spermatogenesis in men,but cannot predict the presence of sperm in testicular tissue samples[J].J Clin Endocrinol Metab,1999,84(7):2496-2501.
-
7Hayes FJ,Pitteloud N,DeCruz S,et al.Importance of inhibin B in the regulation of FSH secretion in the human male[J].J Clin Endocrinol Metab,2001,86(11):5541-5546.
-
8Anderson RA,Wallace AM,Kicman AT,et al.Comparison between testosterone oenanthate-induced azoospermia and oligozoospermia in a male contraceptive study.Ⅳ.Suppression of endogenous testicular and adrenal androgens[J].Hum Reprod,1997,12(8):1657-1662.
-
9Jensen TK,Andersson AM,Hjollund NH,et al.Inhibin B as a serum marker of spermatogenesis:correlation to differences in sperm concentration and follicle-stimulating hormone levels.A study of 349 Danish men[J].J Clin Endocrinol Metab,1997,82(12):4059-4063.
-
10王丽丽,吴燕菁.促卵泡成熟激素和抑制素B在男性生育中的作用[J].国外医学(计划生育分册),2000,19(2):69-72. 被引量:7
共引文献10
-
1程萍,张昌军.抑制素B与生殖[J].生殖医学杂志,2007,16(3):205-208. 被引量:11
-
2董志英,于辉,修贺明,孙辉臣,邱建宏.抑制素B βB亚单位在不同病理分型的无精子症患者睾丸组织中的表达[J].中华男科学杂志,2008,14(1):20-22. 被引量:2
-
3吕晓婷,陈道桢.抑制素B与男性不育[J].中国生育健康杂志,2008,19(5):275-277. 被引量:2
-
4洪文,陈泽林.抑制素B在男性不育症中的应用进展[J].中国社区医师(医学专业),2011,13(25):15-16. 被引量:2
-
5孙雅文,刘亚男,马静,陈京山,闫欢,李京,刘金川,张利新,王永明,汤乃军.TCDD宫内暴露对雄性子代睾丸组织病理学形态和功能的影响[J].毒理学杂志,2015,29(5):352-356.
-
6杨运运,徐计秀,王璟琦,赵阳,廖继强,吴建军.被动吸烟大鼠睾丸组织结构变化与血清抑制素B水平的相关性研究[J].中华临床医师杂志(电子版),2016,10(3):396-400. 被引量:4
-
7胡杨杨,王丽媛,宋博天,陈奥蕾,曹顺顺.不同睾丸活检术对睾丸功能及抗精子抗体的影响[J].中华男科学杂志,2017,23(7):620-625. 被引量:6
-
8朱洪学,童涛.观察血清睾酮(T)/促黄体生成素(LH)、促卵泡激素(FSH)、LH水平检测在临床睾丸生精作用诊断中的临床价值[J].国际检验医学杂志,2018,39(A01):316-318. 被引量:1
-
9高姣,班爽爽,韩梦娜,赵琳,冯蓓,艾庆燕.吸烟对雄性生殖损伤的研究[J].延安大学学报(医学科学版),2018,16(4):86-87. 被引量:1
-
10骆强翔,黄昌平,廖勇彬,郭江华,梁晓东.非梗阻性无精子症患者血清促卵泡刺激素及抑制素B水平与睾丸组织病理分型的相关性[J].山西医药杂志,2021,50(14):2165-2168. 被引量:3
同被引文献11
-
1Bohfing C, Schroeder-Pr~ntzen I, Weidner W, et al. Serum levels of inhibin B and folliclestimulating hormone may predict successful sperm retrieval in men with azoospermia who are undergoing tesfieular sperm extraction[J]. Fertil Ster//, 2002, 78(6) : 1195-1198.
-
2Meachem S J, Nieschlag E, Simoni M. Inhibin B in male repro- duction: pathophysiology and clinical relevance[J]. Euro J Endo- crinoI, 2001,14(5) :561-571.
-
3Jorgez C J, De Mayo F J, Matzuk M M. Inhibin alpha-iCre mice.. Cre deleter lines for the gonads, pituitary, and adrenal[J]. Gene- sis, 2006,4(4): 183-188.
-
4Chand A L, Harrisonl C A, Shelling A N. Inhibin and premature o- varian failure[J]. Hum Reprod Update, 2010,16(1) ,39-50.
-
5de Gouveia Brazao C A, Pierik F H, Erenpreiss Y, et al. The effect of cryptorchidism on inhibin B in a subfertile population[J]. Clin Endocrinol, 2003,59 ( 1 ): 136-141.
-
6Burkart A D, Mukherjee A, Sterneek E, et al. Repression of the inhibin a-subunit gent by the transcription factor CCAAT/enhan- cer-binding protein-[J]. Endocrinology, 2005, 146 ( 4 ): 1909-1921.
-
7Burkart A D, Mukherjee A, Mayo K E. Mechanism of repression of the inhibin ccsubunit gene by inducible 3', 5'-cyclic adenosine monophosphate early repressor [J]. Mol Endocrinol, 2006, 20(3) :584-597.
-
8Kim Y, Kim J S, Song M S, et al. The expression and localization of inhibin isotypes in mouse testis during postnatal development[J]. J Vet Sci, 2008,9(4),345-349.
-
9Halder A, Fauzdar A, Kumar A. Serum inhibin B and follicle- stimulating hormone levels as markers in the evaluation of azoospermic men: a comparison[J]. Andrologia, 2005, 37 (5): 173-179.
-
10Marchetti C, Hamdane M, Mitchell V, et al. Immunolocalizationof inhibin and activin alpha and betaB subunits and expression of corresponding messenger RNAs in the human adult testis[J]. Biol Reprod, 2003,68(1) ,230-235.
-
1王雪云,林伟玲.剖宫产率上升与剖宫产后并发症的研究[J].中外医疗,2009,28(31):63-63. 被引量:3
-
2边旭明,戚庆炜.染色体异常产前筛查和诊断工作任重而道远[J].中国实用妇科与产科杂志,2010,26(12):889-891. 被引量:38
-
3刘彩霞,尹少尉.走中国自己的路 改善多胎妊娠结局[J].中国实用妇科与产科杂志,2015,31(7):579-581. 被引量:3
-
4何吉,朱发明,严力行.孕妇外周血中胎儿DNA在新生儿溶血病产前诊断中的应用[J].国外医学(输血及血液学分册),2005,28(2):144-146.
-
5吴令英,安菊生.宫颈上皮内瘤变的诊治[J].实用妇产科杂志,2013,29(3):170-172. 被引量:18
-
6廖星凤.对优生优育、妊娠及产后护理的浅谈[J].大观周刊,2012(15):102-102.
-
7董丽英.妊娠期高血压并发症患者的临床资料回顾[J].大家健康(学术版),2013(8):135-135.
-
8焦璐璐,马丽蓉,毛建英.肿瘤坏死因子a在妊娠期高血压疾病患者母血及脐血血清中的表达及意义[J].内蒙古医学杂志,2016,48(2):135-137. 被引量:5
-
9孙瑜,朱依敏.高龄不育夫妇,现代辅助生殖技术之惑[J].中国计划生育和妇产科,2014,6(8):1-3. 被引量:24
-
10刘云,张唯力,胡丽娜,徐晓阳.女性内分泌和性功能关系的研究[J].中国性科学,2005,14(5):10-11. 被引量:2