摘要
目的研究清热合剂的解热、抗炎作用。方法分别采用2,4-二硝基苯酚致热大鼠模型、内毒素致热家兔模型、二甲苯致小鼠耳肿胀及蛋清致大鼠足肿胀模型,研究清热合剂的解热、抗炎作用。结果清热合剂可以降低由2,4-二硝基苯酚引起的大鼠体温升高及内毒素引起的家兔体温升高,抑制二甲苯致小鼠耳肿胀及蛋清致大鼠足肿胀。结论清热合剂具有解热、抗炎作用。
Objective To investigate the fever-relieving and anti-inflammatory effects of Qing-Re mixture （QR） for oral use. Methods Animal models of ear edema induced by xylene in mice ,paw edema induced by egg white and fever induced by 2,4-dinitrophenol in rats and endotoxin in rabbits were made,the fever-relieving and anti-inflammatory effects of Qing-Re mixture were studied. Result Qing-Re mixture showed a marked suppressive effects on ear edema induced by xylene in mice, paw edema induced by egg white and fever induced by 2,4-dinitrophenol in rats and endotoxin in rabhits. Conclusion Qing-Re mixture has the anti-inflammation and fever-relieving effects.
出处
《广东药学院学报》
CAS
2006年第1期73-75,共3页
Academic Journal of Guangdong College of Pharmacy
关键词
清热合剂
解热作用
抗炎作用
Qing-Re mixture
fever-relieving effect
anti-inflammatory effect
