肺炎支原体肺炎患儿血清心肌酶活性临床分析

Clinical Analysis of Activity of Serological Myocardial Enzymes in Child with Mycoplasmal Pneumonia

目的:研究血清心肌酶在诊断肺炎支原体肺炎急性期患儿是否有心肌损害的参考价值。方法:测定40例肺炎支原体患儿血清心肌酶磷酸肌酸激酶同功酶(CPK-MB)、乳酸脱氢酶(LDH)和谷草转氨酶(AST)的变化,对其中心肌酶异常的19例患儿在恢复期进行复查,并与40例健康儿童作对照。结果:急性期血清心肌酶明显高于对照组(P<0.01),恢复期血清心肌酶明显下降,CPK-MB,LDH仍高于对照组(分别是P<0.01,P<0.05)。结论:肺炎支原体肺炎急性期可有不同程度的心肌损害,血清CPK-MB作为支原体肺炎心肌损害的生化指标特异性强,治疗支原体肺炎时应注意心肌损害,给予保护心肌治疗。

Objective： To evaluate the value of myeoplasmal enzymes in child with acute mycoplasmal pneumonia. Method： The value of myocardial Enzymes in 40 children were measured, the secondary measur of 19 children in their recovery phase. 40 normal children served as control group. Result： The value of CPK-MB, LDH and AST were slgniticantlly higher than that of contrast group in acute phase （P 〈 0.01）. the value were descended in recovery phase, CKP-MB, LDH still higher than that of contrast. （P 〈 0.01, P 〈 0.05）. Conclusion： Children with myocoplaswal pnenmonia may combine myocardial injures and CPK-MB is a parameter to diagonose the injures. Protection therapy of cardiac muscle should be done for children with myocoplaswal pneumonia.