2－（2－噻唑偶氮）－5－〔N，N－二羧基甲基）氨基〕苯酚的分析特性和钴测定的研究

Analytical Characterization of 2-(2-Thiazolylazo)-5-[(N,N-dicarboxymethyl)-amino] phenol as a Reagent for Cobalt Determination

研究了新显色剂２－（２－噻唑偶氮）－５－［（Ｎ，Ｎ－２羧基甲基）氨基］苯酚（ＴＡＤＣＡＰ）与金属离子的显色反应，着重探讨了试剂与Ｆｅ￣（３＋）、Ｃｏ￣（２＋）、Ｎｉ￣（２＋）、Ｃｕ￣（２＋）、Ｚｎ￣（２＋）、Ｍｎ￣（２＋）显色反应的最佳条件，测定了这些络合物的络合比和稳定常数等，同时建立了钴的分析方法，并用于维生素Ｂ＿（１２）注射液中Ｃｏ￣（２＋）的测定。

In this paper,the reaction of a new water-soluble color reagent,2-(2-thiazolylazo]-5-[(N, N-dicarboxymethyl)-amino] phenol (TADCAP) with some metal ions is described.The optimal acidity for its reaction with Fe(Ⅲ),Co(Ⅱ),Ni(Ⅱ),Cu(Ⅱ),Zn(Ⅱ)and Mn(Ⅱ),the composition ratios and the apparent stability constants of the complexes thus formed have been investigated.The application of this reagent to the spectrophotometrical determination of cobalt in Vitamin B12 injection is presented.