阿扎司琼和氟哌利多预防腹腔镜胆囊切除术后恶心呕吐的效果观察被引量：1

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摘要目的观察阿扎司琼和氟哌利多对腹腔镜胆囊切除手术（LC）患者术后恶心呕吐（PONV）的预防作用.方法 150例ASAⅠ～Ⅱ级LC患者随机分为3组,每组50例,全麻诱导前静脉注射C组生理盐水2ml,B组氟哌利多5mg和A组阿扎司琼10mg.观察3组患者手术结束后0～4小时、5～8小时、9～24小时、25～48小时各时段恶心、呕吐和48小时内头痛、头晕、嗜睡和锥体外系症状的发生情况.结果 3组中A组PONV的发生率最低（P＜0.05）,B组次之;头晕发生率B组明显高于C、A两组（P＜0.05）,头痛发生率B组高于C组（P＜0.05）,C、A两组间无显著性差异,嗜睡的发生率B组高于C组.结论阿扎司琼10mg和氟哌利多5mg静脉注射能明显减少LC患者PONV的发生率,但阿扎司琼10mg效果更佳,不良反应少;使用氟哌利多5mg会增加头痛、头晕、嗜睡的发生率.

作者楼小侃严美娟骆晓攀

机构地区浙江省人民医院

出处《浙江实用医学》 2006年第1期60-61,共2页 Zhejiang Practical Medicine

关键词阿扎司琼氟哌利多腹腔镜胆囊切除术恶心呕吐

分类号 R657.4 [医药卫生—外科学] R442.1 [医药卫生—诊断学]

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