摘要
利尿剂、ACEI和β受体阻滞剂是慢性心衰药物治疗的基础,然而即使规范使用上述药物后,慢性心衰(CHF)预后仍然较差.因此最近几年针对心衰发病中的各种神经内分泌改变开发了一些新的药物,如血管肽酶抑制剂、内皮素拮抗剂、血管加压素拮抗剂和选择性醛固酮拮抗剂等,另外还有免疫调节药物、生长激素、caspase抑制剂和促红细胞生成素等.
出处
《国外医学(老年医学分册)》
2006年第2期57-61,共5页
Foreign Medical Sciences(Geriatrics)
参考文献49
-
1Campbell DJ.Vasopeptidase inhibition:A double-edg-ed sword? Hypertension,2003; 41 (3):383~389
-
2Sheth T,Parker T,Block A et al.Comparison of the effects of omapatrilat and lisinopril on circulating neurohormones and cytokines in patients with chronic heart failure.Am J Cardiol,2002; 90 (5):496~500
-
3Packer M,Califf RM,Konstam MA et al.Comparison of omaptrilat and enalapril in patients with chronic heart failure:The omapatrilat versus enalapril randomized trial of utility in reducing events.Circulation,2002; 106(8):920~926
-
4Nussberger J,Cugno M,Amstutz C et al.Plasma bradykinin in angio-oedema.Lancet,1998; 351 (9117):1693~1697
-
5Pitt B,Zannad F,Remme WJ et al.The effect of spironolactone on morbidity and mortality in patients with severe heart failure.Randomized aldactone evaluation study investigators.N Engl J Med,1999; 341 (10):709~717
-
6Fraccarollo D,Galuppo P,Hildemann S et al.Additive improvement of left ventricular remodeling and neurohormonal activation by aldosterone receptor blockade with eplerenone and ACE inhibition in rats with myocardial infarction.J Am Coll Cardiol,2003; 42 (9):1666~1673
-
7Williams GH,Burgess E,Kolloch RE et al.Efficacy of eplerenone versus enalapril as monotherapy in systemic hypertension.Am J Cardiol,2004; 93 (8):990~996
-
8Pitt B,Reichek N,Willenbrock R et al.Effects of elperenone,enalapril,and eplerenone/enalapril in patients with essential hypertension and left ventricular hypertrophy:The 4E-left ventricular hypertrophy study.Circulation,2003; 108 (15):1831~1838
-
9White WB,Duprez D,St Hillaire R et al.Effects of the selective aldosterone blocker eplerenone versus the calcium antagonist amlodipine in systolic hypertension.Hypertension,2003; 41 (5):1021~1026
-
10Pitt B,Remme W,Zannad F et al.Eplerenone,a selective aldosterone blocker,in patients with left ventricular dysfunction after myocardial infarction.N Engl J Med,2003; 348 (14):1309~1321
同被引文献30
-
1王亚丽,冯惠莲,赵宁.生脉注射液辅助治疗慢性充血性心力衰竭的彩超临床观察[J].中医药学刊,2005,23(5):947-947. 被引量:5
-
2刘尊齐,崔连群,王勇,许法运.血脂康对慢性心力衰竭患者心功能、血清C-反应蛋白和血脂的影响[J].中国中西医结合杂志,2007,27(3):220-222. 被引量:14
-
3张兴平,陈庆伟.慢性心力衰竭大鼠血清细胞因子的变化及其与左室舒张末压的相关性[J].中国老年学杂志,2007,27(14):1348-1349. 被引量:7
-
4南京中医药大学.中药大辞典[M].2版.上海:上海科学技术出版社,2006:991-993.
-
5Morrisen LK, Harison A, Kishnaswamy P, et al. Utility of a rapid Bnatrieric peptide assay in differentiating congestive heart failure from lung disease in patients presenting with dyspnea[J]. J Am Coil Cardio1,2002 ; 39(2) :202-9.
-
6Sola S, Mir MQ, Lerakis S, et al. Atorvastatin improves left ventficular systolic function and serum markers of inflammation in nonischemic heart failure [ J]. J Am Coil Cardio1,2006 ;47 (2) :332-7.
-
7yon Haehling S, Schefold JC, Lainscak M, et al. Inflammatory biomarkers in heart failure revisited:much more than innocent bystanders [ J ]. Heart Fail Clin.2009:5 (4):549-60.
-
8Morrisen LK,Harrison A,Krishnaswamy P,et a1.Utility of a rapid B-natriuretic peptide assay in diferentiating congestive heart failure from lung disease in patients presenting with dyspnea.J Am Coil Cardiol 2002,39(5):202.
-
9Xu X,Wan W,Powers AS,et al.Effects of exercise training on cardiac function and myocardial remodeling in post myocardiacl infarction on rats.J Mol Cell Cardiol,2008,23 (1):114.
-
10Zhang YZ,Xing XW,He B,et al.Effects of testosterone on cytokines and left ventricular remodeling following heart failure.Cell Physiol Biochem,2007,25(6):847.
引证文献5
-
1陈图刚,谭维羚,马战清,钟志英,孙国锋,周宇昕.芪参益气滴丸对慢性心力衰竭患者心功能和细胞因子的影响[J].中国老年学杂志,2011,31(5):742-744. 被引量:40
-
2陈图刚,马战清,钟志英,孙国锋,周宇昕,赵宇.芪参益气滴丸对急性心肌梗死后患者心功能和炎性因子的影响[J].江西医药,2011,46(8):687-689. 被引量:10
-
3吕干.芪参益气滴丸治疗慢性充血性心力衰竭的疗效[J].临床医学,2012,32(12):113-115. 被引量:2
-
4周炜,梁文华.促红细胞生成素对慢性心力衰竭合并贫血的临床疗效观察[J].中国卫生产业,2014,11(29):46-47.
-
5袁海伦.芪参益气滴丸治疗慢性心力衰竭75例疗效分析[J].中国医学工程,2015,23(2):131-131. 被引量:2
二级引证文献51
-
1史铭,丁树根,程湛然,胡梦娟,朱燕,陈丹丹,刘宏.沙库巴曲缬沙坦联合芪参益气滴丸治疗慢性心力衰竭[J].临床心电学杂志,2022,31(6):445-450. 被引量:1
-
2杨清华,邢俊娥,李瑜欣.加味保元汤对慢性心力衰竭患者血管紧张素Ⅱ、肿瘤坏死因子水平的影响[J].中国老年学杂志,2012,32(2):271-272. 被引量:9
-
3刘建,贾静涛.芪参益气滴丸治疗慢性心力衰竭疗效观察[J].中国当代医药,2012,19(6):112-113. 被引量:6
-
4陈炜炜.补阳还五汤对充血性心力衰竭心功能及细胞因子的影响[J].山东中医杂志,2012,31(1):19-20. 被引量:9
-
5张智萃,郭利平.芪参益气滴丸临床应用及实验研究[J].吉林中医药,2012,32(5):514-518. 被引量:8
-
6张晓颖,魏万林,田日新.芪参益气滴丸在心血管系统疾病中的应用进展[J].中国循证心血管医学杂志,2012,4(3):280-281. 被引量:7
-
7张俊岭,李全恩.芪参益气滴丸对舒张性心力衰竭患者血浆中脑钠肽和心功能的影响[J].实用医学杂志,2013,29(1):132-134. 被引量:10
-
8吕干.芪参益气滴丸治疗慢性充血性心力衰竭的疗效[J].临床医学,2012,32(12):113-115. 被引量:2
-
9焦秀清,代升平.芪参益气滴丸治疗慢性心力衰竭的临床观察[J].中国实用医药,2013,8(3):39-40. 被引量:10
-
10滑劲咏.芪参益气滴丸对顽固性心力衰竭患者BNP及心功能的影响[J].中国实用医药,2013,8(4):140-141. 被引量:1
-
1孙凌云.CD4^+CD25^+调节性T细胞—免疫治疗新策略[J].中华风湿病学杂志,2008,12(3):145-147.
-
2凌兰.房颤治疗新策略[J].中国保健营养,2011(10):92-94.
-
3雷闽湘.2型糖尿病治疗新策略:基于肠促胰素的治疗[J].国际内分泌代谢杂志,2009,29(6):370-373. 被引量:2
-
4Ball,P.慢性支气管炎治疗新策略和喹诺酮类应用的争议[J].国外学者来访报告,1998,18(2):23-23.
-
5胡学.2型糖尿病治疗新策略格华止降糖地位再评估[J].世界医学杂志,2001,5(10):76-76.
-
6白燕,周庆元.支气管哮喘治疗新策略[J].医学综述,2008,14(23):3615-3618. 被引量:5
-
7施桂英.类风湿关节炎的治疗新策略[J].中华内科杂志,1991,30(10):605-606. 被引量:9
-
8张定凤教授提出抗病毒治疗新策略[J].传染病网络动态,2001(10):18-19.
-
9Henry Krum Markus Schlaich Paul Sobotka Ingrid Scheffers Abraham A.Kroon Peter W.de Leeuw 童保文 林志鸿 谢良地.以手术和器械装置为基础的难治性高血压的治疗新策略[J].中华高血压杂志,2012,20(1):86-90.
-
10张炜,魏继红,李文格.糖尿病肾病的预防及治疗[J].实用糖尿病杂志,2007,3(2):58-59. 被引量:3