摘要
目的:探讨痰热清对急性胰腺炎(AP)合并急性肺损伤(ALI)患者的治疗作用。方法:79例AP病例,53例采取常规治疗,26例加用痰热清治疗,观察ALL／急性呼吸窘迫综合征的发生率,并记录血气指标和外周血IL-6,IL-8及TNF-α水平。结果:常规治疗组和痰热清治疗组ALI发生率分别为56．6％和30．8％(P<0．05);痰热清治疗组之PaO2和PaO2／FiO2高于非痰热清治疗组;患者外周血TNF-α、IL-6和IL-8在痰热清治疗后显著下降(P<0．05)。结论:痰热清能有效降低AP患者急性肺损伤的发生率,改善ALI/ARDS时的低氧血症状态。
Objective： To explore the effect of tanreqing injection on acute pancreatitis （AP） with acute lung injury （ALI）. Method： In 79 cases with AP, 53 cases accepted routine therapy of AP, and the orther 26 cases added tanreqing injection. Incidence of ALI and acute respiratory distress syndrome （ARDS） were observed, blood gas analysis and levers of IL-6, IL-8 and TNF-α in peripherial blood were tested and recorded. Result： Incidence of ALI/ARDS and the levers of IL-6, IL-8 and TNF-α in tanreqing group were much lower than that in routine group （P 〈 0.05）, and PaO2 and PaO2/FiO2 were higher than the routine control group. Conclusion： Tanreqing injection can decrease the incidence of ALl and ARDS in patients with AP and improve hypoxemia.
出处
《中国药师》
CAS
2006年第3期225-226,共2页
China Pharmacist
关键词
胰腺炎
肺损伤
痰热清
Acute pancreatitis
Acute lung injury
Tanreqing
