老年肺心病并发肺部真菌感染32例临床分析

Pulmonary fungal infection with chronic cor pulmonale in 32 elderly

目的探讨老年肺源性心脏病(肺心病)患者肺部真菌感染(PFI H)的发病因素、病原学分布及其临床诊治。方法对32例老年肺心病并发PFI H患者的临床资料进行回顾性分析。结果老年、住院日的延长、抗生素及激素的不合理应用、医源性侵袭性操作易导致真菌感染(与对照组比较P<0.05或<0.01);在分离的真菌中,以白色念珠菌为主(占73.52%),其他真菌分离率均小于10%。结论老年肺心病PFI H呈上升趋势,减少或避免可能导致真菌感染的各种因素,并采取有效的防治措施刻不容缓。

Objective To investigate the etiology distribution,and treatment in pulmonary fungal infection （PFIH） accompanied with cot pulmonale in the elderly. Methods Clinical data of 32 PFIH cases with cot pulmonale in elderly were collected and retrospectively analyzed. Results Aging,extension of hospitalization,overuse of antibiotics or steroids,invasive operation were apt to fungal infection （ P 〈 0.05 vs. control）. Pathogenic identification showed that white moniliform was predominant in 73.52%,while others were less than 10%. Conclusions There were increasing infection with PFIH in cot pulmonale in elderly. Effective treatment should be taken to handle it.