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AMWH与福辛普利联合治疗糖尿病肾病疗效观察 被引量:5

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摘要 将64例2型糖尿病肾病(DN)患者随机分为治疗组(低分子量肝素+福辛普利)32例,对照组(福辛普利)32例。比较两组治疗前和治疗后7周尿微量白蛋白排泄率(UAER)、血肌酐(Scr)、总胆固醇(TC)、甘油三酯(TG)等指标的变化。结果两组经治疗后UAER均显著下降(P<0.05,P<0.01),治疗组比对照组下降更明显(P<0.05)。治疗组治疗后Scr、TC、TG水平下降,与治疗前相比有显著性差异(P<0.05);对照组治疗后Scr、TC、TG无明显改变(P>0.05)。两组经治疗后血尿素氮(BUN)、空腹血糖(FBG)、平均动脉压(MAP)均无明显变化。认为低分子量肝素与福辛普利联合能有效地减少DN患者的蛋白尿,改善肾功能。
出处 《山东医药》 CAS 北大核心 2006年第7期36-37,共2页 Shandong Medical Journal
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