摘要
目的:探讨诸多临床因素对脑膜瘤复发的影响。以便能有效地早期预防和控制脑膜瘤复发,改善其预后。方法:回顾经神经外科手术治疗脑膜瘤患者145例,对其临床诊治过程进行回顾性分析,发现其中资料齐全的有83例,分析其临床因素如性别、年龄、术前KPS(KarnofskyPerformanceScale)评分、术后KPS评分、手术切除程度、组织学类型、肿瘤形状、肿瘤大小、骨质改变,应用SPSS11.07软件,进行单因素分析和多因素分析。多因素分析应用二值多元Logic回归模型,以诸多临床因素作为自变量,复发与否作为因变量。结果:经单因素分析显示肿瘤形状、肿瘤大小、组织学类型、手术切除程度与脑膜瘤复发有明显关系。多因素分析显示肿瘤形状、组织学类型、手术切除程度是影响脑膜瘤复发的主要因素。其它因素在单因素分析及多因素分析中均显示对脑膜瘤复发无明显影响。结论:脑膜瘤手术切除程度、组织学类型、肿瘤形状对脑膜瘤复发有明显影响,可作为预测脑膜瘤复发的显著危险因子和标准。
Objective： To provide reasonable evidences of the clinical factors that affect the recurrence of meningioma so as to diagnose and treat the recurrence of meningioma earlier. Methods： Clinical features in 83 cases of meningiomas, which were operated during 1993-1997, were studied retrospectively. The factors were evaluated with univariate and multivariate analysis. Results： With univariate analysis, four factors highly related to the recurrence of meningiomas. They were tumor size, tumor shape, extent of resection and pathological grade. Pathological grade, extent of resection and tumor shape were risk factors of meningiomas recurrence with multivariate analysis. Conclusion： The main factors that affect the recurrence of meningioma patients are pathological grade, extent of resection and tumor shape.
出处
《武汉大学学报（医学版）》
CAS
2006年第2期263-265,268,共4页
Medical Journal of Wuhan University
关键词
脑膜瘤
危险因素
复发
Meningioma
Risk Factors
Recurrence
