摘要
弥漫性大B细胞淋巴瘤(DLBCL)是一类异质性的B细胞性恶性淋巴瘤,其组织形态、免疫表型、分子遗传学特点及预后各异。近年来,对DLBCL进行了大量免疫组化和分子生物学研究,并试图对其进一步分型。作者综述DLBCL的形态学、免疫组化、分子生物学特点及与预后的关系。
Diffuse large B-cell lymphoma (DLBCL), the largest category of lymphoma, is a clinically and biologically heterogeneous disease entity. Immunophenotype, tissue microarray and molecular studies underline the extreme heterogeneity of DLBCL and suggest a subclassification of the tumor. This review summarizes the morphological, immunophenotypic, cytogenetic and molecular genetic features of DLBCL relevant to the precise prognostic previsions.
出处
《医学研究生学报》
CAS
2006年第3期277-280,共4页
Journal of Medical Postgraduates