汉密顿抑郁量表6项版本(HAMD-6)的信度及效度研究

The validity and reliability of the six-item Hamilton Depression Rating Scale.

目的检验汉密顿抑郁量表6项版本（HAMD-6）的信度与效度。方法选用汉密顿抑郁量表6项版本（HAMD-6）与24项版本（HAMD-24）对264例住院及门诊抑郁症患者和32名正常对照进行了评定；并对随机抽取的34例住院患者在第1次评定后3天进行第2次评定；由经培训的2名评定员对其中的10名抑郁症患者同时施行量表评定，进行评分者信度研究；将HAMD-6与另3个版本（17项、21项、24项）进行相关分析，进行效度研究。结果HAMD-6的内部一致性系数Cronbach’s的α为0．474，条目间的平均相关系数为0．131，34例患者重测HAMD-6的相关系数为0．951（P〈0．01），评定员HAMD-6相关系数为0．989（P〈0．01）；HAMD-6各条目与总分的相关系数r在0．294-0．645之间（P〈0．01）；患者组同正常对照组HAMD-6总分经t检验，差异具有显著性（P〈0．01）；264例抑郁症患者HAMD-6总分与另3个版本总分显著相关，r为0．638-0．683（P〈0．01）。结论HAMD-6同广泛使用的其他版本一样具有较高的信度与效度，并由于条目简洁，操作方便，易于掌握和节省时间，值得在临床推广使用。

Objective To explore the validity and reliability of the 6 - item Hamilton Depression Rating Scale （HAMD-6）. Methods A sample of 264 patients with depression and32 normal controls were evaluated the HAMD-6 and HAMD-24. The internal reliability and test - retest reliability were examined. A sample of 10 patients with depression were evaluated the HAMD-6 between two trained psychiatist in order to assess the scorer reliability, evaluate the total scale scores of the HAMD-6 between depression patients and normal control. Result The Cronbach＇s α coefficient of the HAMD -6 was 0. 474; The mean interitem correlation coefficients was 0. 131 ;The test - retest reliability of HAMD-6 was 0. 951 ; The scorer reliability coefficient were 0. 989 ;The range of correlation coefficient of the six item with the total score of the scale was 0. 294-0. 645 ; The total scale scores of the HAMD-6 in depression patients were significantly higher than those in normal conubl ; There were strong correlation between the four versions of the HAMD for all subjects. Conclusion The present finding indicated that the HAMD-6 is a reliable and valid measure for assessing depression. The ease of administration and the minimal time requirement also support its incorporation into routine clinical practice.