包皮冠状沟皮肤袖状切除术治疗阴茎冠状沟多发尖锐湿疣35例报告

Treatment of Multiple Condyloma Acuminatum of the Coronary Sulcus with Sleeve Circumcision of Prepuce and Coronary Sulcus Skin (a Report of 35 cases)

目的:观察包皮冠状沟皮肤袖状切除术治疗阴茎冠状沟多发尖锐湿疣(CA)的临床疗效。方法:采用随机分组对照临床研究方法,治疗组35例患者行包皮及冠状沟皮肤袖状切除术,对照组34例患者行疣体电灼术及传统包皮环切术。结果:治疗组术后平均10.2d拆线,无并发症。对照组平均8.1d拆线,电灼创面平均19.4d愈合。随访6个月,治疗组CA复发率5.7%,对照组为26.5%,差异有显著性(P=0.0438)。结论:包皮冠状沟皮肤袖状切除术治疗阴茎冠状沟多发CA的疗效优于疣体电灼术加传统包皮环切术。

Objective： To evaluate the effectiveness of sleeve circumcision of prepuce and coronary sulcus skin in the treatment of patients with multiple condyloma acuminatum （CA） of coronary sulcus of penis. Methods ： In a randomized clinical control study, 35 patients were randomsized to the treatment group and received sleeve circumcision of prepuce and coronary sulcus skin. 34 patients were randomsized to the control group, received electric cauterization of verrucae plus the general circumcision. The recurrence of CA was evaluated in follow-up visit within three monthes after the treatment. Results： The stitches were taken out 10.2 days after opera- tion in the treatment group, and 8.1 days in the control group. There were no complication in the treatment group,the average healing time of electric cauterization wound was 19.4 days in the control group. There was a statistically significant difference in the recurrence rate of CA between the treatment group and the control group （5.7% vs 26.5%, P 〈 0.05 ）. Conclusions ： The sleeve circumcision of prepuce and coronary sulcus skin is more effective than electric cauterization of verrucae plus the general circumcision in the treatment of oatients with multiole condyloma acuminatum of coronary sulcus of penis. Natl J Androl,2006,12 （3） ：240-242,246