用背心式呼吸感应体积描记系统实现通气量无创测量

Non-invasive Ventilation Measurement with a Wearable Respiratory Inductive Plethysmography

以背心式呼吸感应体积描记系统为平台,经过标定实现通气量的无创测量,并检验测量结果的准确性。用背心式呼吸感应体积描记系统和呼吸速度描记仪同时记录15名受试者的呼吸数据,取前5min数据用诊断性定性校正技术(qualitative diagnostic calibration,QDC)标定背心式呼吸感应体积描记系统,后续数据用于对比检验背心式呼吸感应体积描记系统测量通气指标的准确性及有效性。结果表明,15组对比检验数据,背心式呼吸感应体积描记系统经过标定所测平均潮气量(总体平均潮气量为443±79ml)与呼吸速度描记仪所测平均潮气量(总体平均潮气量为446±83ml)相关性很好(R=0.9988,P<0.001,n=15),对两种方法所测平均潮气量进行t检验,P=0.918,说明两种测量方法在平均潮气量测量上无统计学差异。15组数据中,两种方法所测平均潮气量相对误差最大值为2.42%,比较逐呼吸潮气量,在15组数据共11 437次呼吸中,93.85%的点(10 734次)的相对误差落在10%之内,98.10%的点(11 220次)的相对误差落在15%之内,99.03%的点(11 326次)的相对误差落在20%之内。背心式呼吸感应体积描记系统采用诊断性定性校正技术标定后,能够准确测量通气指标,此系统是实现长时间、低负荷、动态呼吸模式监测的有效方法。

To design a non- invasive respiratory volume measurement with the new wearable respiratory inductive plethysmography system （RIPvest） using the qualitative diagnostic calibration （QDC） method. Tidal volumes（VT ） from the RIPvest were compared with the simultaneous pneumotachometer（PTM） volumes in 15 healthy subjects in supine position after the first five minutes＇ QDC calibration. Result showed that the mean tidal volume measured by the RIPvest（443 ± 79ml） correlated well（ R= 0.9988, P 〈 0.001, n = 15） with the mean tidal volume measured simultaneously by PTM（446 ± 83ml） on 15 validation runs. Average RIPvest and PTM values did not differ significantly （P = 0.918）. Of the 11 437 validation breaths, 10 734（93.85%）were within ± 10% of the simultaneously measured PTM volume, 11 220（98.10%）were within ± 15 %, and 11 326（99.03 % ） were within ± 20%. These findings suggest that this new wearable respiratory inductive plethysmography system can be considered a quantitative method for measurement of tidal volume, it is a new, simple and non - intrusive method for long time ambulatory respiratory pattern monitoring.