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胸腺近期输出功能与移植后T细胞免疫重建

Recent thymic output function and T cells immune reconstitution after transplantation
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摘要 造血干细胞移植的成功,有赖于T细胞免疫的重建。T细胞受体重排删除环(TRECs)是目前较可靠的反映胸腺近期输出功能的检测指标。定量检测TRECs水平可判断胸腺近期输出功能,评价移植后T细胞免疫重建情况。 Successful hematopoietic stem cell transplantation depends on T cells immunol reconstitution. At present, the T-cell receptor excision DNA circles （TRECs）is the reliable index to monitor recent thymic output function. Quantitative analysis of TRECs level can determine the recent thymic output function and evaluate T cells immune reconstitution after transplantation.
作者 吴秀丽 朱康儿 李扬秋
机构地区 暨南大学医学院血液病研究所
出处 《肿瘤研究与临床》 CAS 2006年第3期209-211,共3页 Cancer Research and Clinic
基金 国家自然科学基金资助(30270579) 广东省自然科学基金重点项目(23001) 广东省教育厅"千百十工程"优秀人才培养基金(校级)项目(Q校02022)
关键词 胸腺近期输出功能 造血干细胞移植 T细胞免疫重建 Recent thymic output function Hematopoietic stem cell transplantation T cells immunal reconstitution
分类号 R392 [医药卫生—免疫学]
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参考文献23

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二级参考文献13

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肿瘤研究与临床
2006年 第3期

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