负性生活事件与老年抑郁症发病率的关系

Relationship of Life Events and the Incidence of Geriatric Depression

目的探讨负性生活事件和老年抑郁症发病率的关系。方法以GMS-AGECAT与MDS量表为调查工具,对基线调查时确定的非抑郁老年人进行队列研究。采用χ2检验、Spearman相关分析和多元Logistic回归分析来分析数据。结果随着负性生活事件发生数增加,老年抑郁症发病率增高,两者有密切相关(r=0.96,P<0.01)。χ2检验表明,健康恶化、经济困难、难过事情、亲友冲突、恐怖经历发生与否与老年抑郁症发病率关系达显著性水平(P<0.01)。多元Logistic回归分析表明,经济困难(RR=1.82)、亲友冲突(RR=5.18)对老年抑郁症发病率有显著性影响(P<0.01)。结论负性生活事件与老年抑郁症发病率密切相关,经济困难、亲友冲突是老年抑郁症的危险因素。

Objective： To examine the relationship of negative life events and the incidence of geriatric depression. Methods： Non-depressed elderly of a study on the prevalence of depression among the elderly was followed upwith a one-year interval with the GMS-AGECAT and MDS. The data was analyzed by SPSS using x^2 analysis, correlateanalysis and Muhinomial Logistic Regression. Results： The incidence of geriatric depression had close relationshipwith the number of negative life events （ r =0. 96, P 〈 0. 01）. There was significant difference of incidence of geriattic depression between the elderly who experienced the health deteriorating, economy trouble, painful things, conflictwith frienda/relatives/children and horrible experiences and those who didnt （chi square test, P 〈 0.01） . Economytrouble （ RR 1.82） and conflict with friends/relatives/children（ RR 5.18） were main factors shown by Logistic analysis （ P 〈 0.01 ）. Conclusion ： Negative life events have very close relationship with the incidence of geriatric depression. Economy trouble and conflict with friends/relatives/children are risk factors.