沉香的化学成分研究(Ⅰ)

A novel triterpenoid saponin from bulbs of Bolbostemma paniculatum

目的研究沉香中2-(2-苯乙基)色酮类成分。方法沉香乙醇提取物的乙醚部位,用硅胶柱色谱,以石油醚、醋酸乙酯不同比例梯度洗脱,分得2个成分,通过理化常数和光谱分析鉴定化合物的结构。结果从沉香乙醇提取物中分得2个色酮类成分,分别鉴定为6,8-二羟基-2-[2-(3′-甲氧基-4′-羟基苯乙基)]色原酮{6,8-dihydroxy-2-[2-(3′-methoxy-4′-hydroxylphenylethyl)]chromone,}和6-甲氧基-2-[2-(3′-甲氧基-4′-羟基苯乙基)]色原酮{6-methoxy-2-[2-(3′-methoxy-4′-hydroxylphenylethyl)]-chromone,}。结论化合物为新化合物,化合物为已知化合物。

Objective To study the chemical constituents of Aquilaria sinensis. Methods Column chromatographic technique was employed for the isolation and purification of its constituents by solvent, the ether fraction of ethanol extract of A. sinensis was conducted gradient elution by petroleum ether and ethyl acetate in different proportions. Their structures were identified by physicochemical constant and spectral analysis （IR, UV, EI-MS, ^1H-NMR, ^13C-NMR, and HMBC）. Results The compounds were identified from their ethanol extracts as： 6, 8-dihydroxy-2-[2-（3＇-methoxy-4＇-hydroxyl phenylethyl）] chromone （ Ⅰ ） and 6-methoxy-2- E2- （3＇-methoxy-4＇-hydroxyl phenylethyl） ] chromone （ Ⅰ ）. Conclusion Compound Ⅰ is a novel compound and Ⅱ is a known one.