冰冻切片诊断在甲状腺手术中的临床应用

Clinical Application of Frozen Section in Thyroid Operation

目的探讨冰冻切片在甲状腺手术中的临床应用,提高甲状腺冰冻切片诊断的准确率,减少甲状腺恶性肿瘤的漏诊。方法回顾性对比观察248例甲状腺冰冻切片和石蜡切片。结果冰冻切片诊断良性病变217例,恶性肿瘤22例,延迟9例;石蜡切片对照良性病变220例,恶性肿瘤28例,其中冰冻切片假阴性诊断3例(1.21%),冰冻切片确诊率为95.16%。结论提高切片质量,掌握正确的取材方法,提高对甲状腺良恶性肿瘤的识别和鉴别能力,可提高甲状腺手术中冰冻切片诊断的准确率。

Objective To discuss the clinical application of frozen section in thyroid operation so as to raise the rate of correct diagnosis. Methods A retrospective review was made to 248 frozen sections and paraffin sections. Results The frozen section diagnosis showed out 217 eases with benign lesion,22 eases with malignant tumor and there were 9 delayed diagnosis;in the control, the paraffin section showed 220 cases with benign lesion and 28 eases with malignant tumor;There were 3 false-negative diagnosis by frozen section （ 1.21% ） and conformed diagnosis rate of frozen section reached 95. ] % . Conclusions The correct diagnosing rate of frozen section in thyroid operation may be raised by increasing the section quality and improving the method.