神经营养素脑内功能及其表达调节

Function and Expression Regulation of Neurotrophins in Brain

神经营养素（ｎｅｕｒｏｔｒｏｐｈｉｎ，ＮＴ）是与神经生长因子同源的一类神经营养因子，它们在神经系统的分化和发育过程中起着重要作用，并具有治疗某些脑疾病的潜在应用价值．文章较全面地阐述了ＮＴ在脑内既相互交叉又有各自特性的生理功能，并系统地介绍了脑内ＮＴ表达调节方面的研究进展．

A family of neurotrophic factors homologous to nerve growth factor (NGF) is designated by the name of neurotrophins. They play important roles in the differentiation and development of nervous system and might haveclinical potential in the treatment of neurodegenerative diseases. The recent advances in reciprocal but distinctive physiological roles of the neurotrophins and their expression regulation in brain are summarized.