笑气吸入加利多卡因宫颈注射用于人工流产120例疗效分析

Therapeutic analysis of inspired nitrous oxide with injecting lidocarine in cervical uterus for 120 cases of women with artificial abortion

目的:比较笑气、利多卡因联合应用和笑气单用时对人工流产镇痛、宫口松驰等的临床效果及人工流产综合征等不良反应的差异。方法:对240例孕45～70d自愿要求人工流产的健康妇女随机分为观察组和对照组。观察组120例术中使用50%氧化亚氮和50%氧气的混合气体(笑气)吸入,并于宫颈注射2%利多卡因2mL加生理盐水2mL,对照组单用笑气吸入。结果:观察组的镇痛显效率为69.2%,宫颈松驰度显效率为56.7%,均明显高于对照组(均P<0.005),人工流产综合征发生率及不良反应发生率无显著性差异(均P>0.05)。结论:笑气联合利多卡因用于人工流产较单用笑气镇痛、宫口松驰效果更好,且使用简单安全。

Objective： To compare the analgesia and relaxation of uterus ostium etc. clinical effects and the side reaction of abortion syndrome between use of nitrous oxide with injecting lidocaine in cervical uteri and nitrous oxide only for artificial abortion. Methods ：240 cases of healthy women,having pregnancy for 45 to 70 days,were randomly divided into treatment and control groups. Inspired nitrous oxide with injecting lidocaine（2% lidocaine 2ml adding 2ml physiological saline）in cervical uteri in treatment group （n=120）;Inspired nitrous oxide only in control group（n=120）. Results： The obvious effective rates for both analgesia and relaxation of uterus ostium were 69.2% and 56.7% respectively in the treatment group; They were significantly higher than that of control group（P〈0.005）.The genesis rates of both abortion syndrome and side reaction had no significantly differences between two groups （P〉0.05）. Conclusion： Inspired nitrous oxide with lidocaine injection show better analgesia and relaxation of uterus ostium compared with nitrous oxide only for artificial abortion. Its use is simple and safe.