解脲支原体和人型支原体的药敏分析

Sensitivity of Ureaplasmsa Urealyticum And Mycoplasma Hominis to Antimicrobial Agents

【目的】了解解脲支原体(Uu)和人型支原体(Mh)的耐药状况,指导临床合理用药。【方法】应用支原体培养鉴定药敏试剂盒进行检测。【结果】512例门诊患者,251例支原体培养阳性,阳性率49.02%;Uu单项感染164例(32.03%)显著高于Mh感染(17例3.32%)和Uu+Mh混合感染(70例13.67%)(P<0.01);药敏结果显示,以交沙霉素和强力霉素敏感性最强(90.04%,89.24%),其次为司帕沙星和克拉霉素(70.92%,69.32%),而对环丙沙星、可乐必妥和红霉素敏感性较差。【结论】选择敏感有效的抗生素对于控制支原体的传播和蔓延尤为重要。

[Objective] To investigate drug resistance of Ureaplasma urealytieum （Uu） and Mycoplasma hominis（Mh） to provide basis for reasonable use of antibiotics in clinical practice. [Methods]The kit for mycoplasma culture and drug sensitivity detection was used. [Results]Amongst the 512 patients, 251 were positive for the detection of mycoplasma and the positive rate was 49. 02%. The number of patients with Uu infection was significantly higher than that of patients with Mh infection or mixed Uu and Mh（P〈0.01 ）. The mycoplasma had the highest sensitivity to josamycine and doxycycline, followed by spaxacin and clarithromycine. Howere , they were not sensitive to ciprofloxacin,cravit, erythromycin. [Conclusion]Selection of sensitive and effective antibiotics is very important for controlling myeoplasma transmission and spreading.