凯时注射液治疗脑梗死的临床观察

Therapeutic Effect of Prostaglandin E_1 Injection to Acute Cerebral Infarction

【目的】探讨凯时注射液治疗脑梗死的疗效。【方法】选择脑梗死患者58例,分为治疗组35例及对照组23例。治疗组采用凯时注射液10μg,静脉滴注,每日1次,疗程为15d。对照组采用复方丹参注射液20ml,静脉滴注,每日1次,疗程同治疗组。【结果】治疗组神经功能缺损评分积分下降明显,与对照组相比差异有显著性(P<0.01),脑梗死体积减少程度与对照组相比差异亦有统计学意义(P<0.05)。【结论】凯时注射液对脑梗死疗效显著,能降低致残率,改善脑梗死预后。

[Objective]To observe the therapeutic efficacy on Kai Shi（prostaglandin E1 ） to cerebral infarction. [Methods]Fifty eight patients with cerebral infarction were selected. They were divided into two groups at random： 35 patients in therapy group and 23 patients in control group. The therapy group was injected with Kai Shi once everyday for 15 days and the control group was injectcd with dan shen composite once everyday. [Results]There was significant difference between the therapy group and the control group with neurologic impairment score and cerebral infarction volume change after therapy （ P〈0.01and P 〈0.05, respectively）. [Conclusion]Prostaglandin E1 is effective in the therapy of acute cerebral infarction. It can reduce the mutilation rate and improve the prognosis of cerebral infarction.