血清脂蛋白(a)的检测与老年心血管疾病的相关性探讨

Discussion of Relationship Between Serum Lipoprotein (a) Examination and Senile Cardiovascular Disease

【目的】探讨血清脂蛋白(a)[LP(a)]在老年人高血压病、老年人急性心肌梗死(AMI)、老年人肥胖中的诊断价值。【方法】采用免疫透射比浊法检测老年人LP(a)的含量,其中AMI组40例;高血压病组64例;肥胖组24例及健康对照组50例。【结果】AMI组及高血压病组的LP(a)含量与健康对照组比较差异均有显著性(P<0.01),老年肥胖组与健康老年人对照组比较差异也有显著性(P<0.05)。【结论】老年人LP(a)的水平与老年人高血压、老年人AMI密切相关,是老年人心血管疾病诊断的一个重要指标,高LP(a)水平可作为老年人心血管疾病的危险因子之一,临床上应重视LP(a)的检测。

[Objective]To discuss diagnostic value of serum lipoprotein （a）[ LP （a）] in senile hypertension, acute myocardial infarction （AMI） and obesity . [Methods]Serum LP（a） was detected by immunity transmission turbidimetric method in 40 AMI, 64 hypertension 24 obese patients and 50 healthy controls. [Results]The LP（a ） levels of AMI,hypertension,obesity cases were higher than those of control, there was significant difference （ P 〈0.05 or P 〈0.01）. [Conclusion]The level of serum LP（a） is closely associated with AMl,hypertension. High level of LP（a） may be diagnostic marker and risk factor of cardiovascular diseases in senile cases. Physician should pay attention to detect LP（a） in senile patients.