126株肺炎链球菌临床菌株的耐药率分析

Antimicrobial resistance of 126 strains of Streptococcus pneumoniae

目的调查呼吸道感染肺炎链球菌对常用抗生素的耐药情况。方法肺炎链球菌用全自动细菌鉴定仪及GPI卡鉴定,药敏试验采用琼脂扩散法。结果126株肺炎链球菌中,青霉素耐药的肺炎链球菌(PRSP)占16.7%,青霉素中度敏感的肺炎链球菌(PISP)占23.0%,肺炎链球菌对红霉素、复方磺胺甲口恶唑、克林霉素的耐药率分别为69.0%、67.5%和65.9%。结论我院呼吸道感染肺炎链球菌对青霉素的耐药率较低,其不敏感性以PISP为主。

Objective To investigate antimicrobial the resistance of Streptococcus pneurnoniae （ S. pneurnoniae）. Methods 126 S. pneurnoniae strains were collected and identified by VITEK-32. Susceptibility to antibiotics was determined by disc diffusion test. Results The positive rates of penicillin-reslstant S. pneumoniae（PRSP） and penicillin-intermediate S. pneumoniae（PISP） were 16.7% and 23.0% respectively. The resistance rates to erythromycin, sulfamethoxazole and clindamycin were 69.0% ,67.5% and 65.9% respectively. Conclusions The penicillin-resistant rate of S. pneumoniae is low,in which PISP is the majority.