证候规范化研究的思路和方法探讨

Exploration on Thinking Approach and Methodology of Syndrome Standardizat ion

采取“降维降阶”、“升阶升维”的研究思路,既排除非关键因素的干扰,又能真实反映证候的复杂程度,是证候规范化研究的可行途径。借助古代大型医案数据库,对部分证候及其相关因素进行统计分析,采用国际通用的SAS6.12统计软件中的非条件Logistic多元逐步回归方法筛选变量,最终获得回归方程数学模型,表达为logit(p)=α+β1X1+β2X2+…+βmXm。通过该模型的运用和统计数据结果的分析,对具有诊断意义的证候内容进行规范化研究,为证候诊断的规范化提供参考。

The researching thinking approach of ＂descending the dimension with the lowering rank, ascending the rank with the raising of nsion of dimension＂, which could exclude the intervention of non-crucial fact ors and reveal the complexity of syndrome as well, provides a feasible approach for syndrome standardization. A study was conducted by analyzing some syndromes and their correlated factors selected from the ＂Ancient Good-sized Medical Records Database＂ through unconditional logistic multivariate stepwise regression by SAS 6.12 universal statistical software to sieve the variable, and the mathematical mode of regression equation was obtained eventually, expressed as logit （p） =α ＋ β1X1 ＋β2X2 ＋… ＋ βmXm, With that, the research of syndrome standardization was proceeded on the syndromes with diagnostic significance to provide references for standardization of syndrome differentiation.