早期综合干预对脑功能障碍性综合征患儿智力发育的影响

Early comprehensive intervention on intelligence development in infants with brain disorder syndrome

目的探讨早期综合干预对改善脑功能障碍性综合征患儿预后的效果。方法82例脑功能障碍性综合征患儿随机分为干预组和对照组。干预组予以医学干预、早期干预、营养干预及康复治疗等早期综合干预；对照组常规育儿。患儿3、6、12月时均进行智力测定。结果 3、6、12个月干预组平均发育商分别为80．2±14．2、95．1±13．4、112±10．4，对照组平均发育商为68．6±12．3、80．0±15．4、85．4±16．3，T值分别为3．89、4．75、8．89，干预组发育商明显高于对照组（t=3．89～8．89，P〈0．01）。结论早期综合干预能有效的促进脑功能障碍性综合征患儿智能发育。

Objective To explore prognostic effects of early comprehensive intervention on intelligence development in infants with brain disorder syndrome. Methods Eighty-two children with brain disorder syndrome were randomly divided into two groups （the intervention group and control group）. Early comprehensive intervention including medical intervention, early intervention, nutrition intervention and convalescent care was performed in the intervention group. The infants of the control group was healthy. Detection of intelligence was performed in intervention group in the 3rd, 6th and 12th month. Results Mean growth quotient of the 3rd, 6th and 12th month was 80.2± 14.2,95.1 ± 13.4 and 112 ± 10.4, respectively. Mean developing quotient of the 3rd, 6th and 12th was 68.6 ± 12.3,80.0 ± 15.4 and 85.4 ± 16. 3, respectively. T value was 3.89,4. 75 and 8.89, respectively. Mean developing quotient in the intervention group was better than that in the control group （ t = 3. 89- 8.89 , P 〈 0.01 ） . Conclusion Early comprehensive intervention can promote effectively intellectual development in children with brain disorder syndrome.