摘要
目的对湘西地区大肠癌进行临床病理探讨。方法１９７９＿１９９４年经手术治疗的大肠癌３５４例进行临床及病理分析。结果早期以慢性肠道炎症症状、腹痛为主，职业以务农为多，部位以直肠最多，组织学以腺癌最多。环境污染因素与慢性炎症是本地区大肠癌发病的主要因素。结论有肠道症状时要进行“一指四查”，必要时活检检查等。
AIMS To study the large intestinal cancer clinico_pathologically in western Hunan. METHODS From 1979 to 1994, 354 cases of large intestinal cancer proved by surgery were analyzed retrospectively. RESULTS They were 194 males 40 or older and 160 females (male/female ratio 1.21∶1). with age range from 17 to 77 (mean 40.1) years. Fifty_eight percent of the patients were. Sixty percent of the patients were peasants. Most of the cancers (67.2%) were located in the rectum. The symptoms of chronic colitis and abdominal pain were the most common early clinical manifestations. Microscopically adenocarcinoma(82.8%) and signet ring cell carcinoma(11.6%) were common. The risk factors were enviromental pollution and chronic inflammation of the colon. CONCLUSIONS Rectal digital examination, occult blood test, colonfibroscopy, barium enema cytology, biopsy and immunohistochemical technique should be done if needed.
