摘要
目的观察还原型谷胱甘肽(TAD)对病毒性肝炎的疗效。方法治疗组46例,其中慢性肝炎25例,给以TAD600mg,加入10%葡萄糖液500ml中,静脉滴入,1次/d。对照组46例,共中慢性肝炎25例,给以门冬氨酸钾镁1g,加入10%葡萄糖液500ml中,静脉滴入,1次/d。共2个月。结果治疗组慢性肝炎有效率为80.0%;急性肝炎21例,有效率为85.7%,急慢性肝炎总有效率为82.6%。对照组慢性肝炎有效率为60.0%;急性肝炎21例,有效率为66.7%,急慢性肝炎总有效率为63.0%。两组差异显著(P<0.05)。
AIMS To observe the effect of reduced glutathione(TAD) on viral hepatitis. METHODS Fourty_six patients with acute or chronic viral hepatitis were treated with TAD(600mg in 10% glucose solution) infusion every day for 2 months, and other 46 patients with acute or chronic hepatitis were treated with potassium_magnesium aspartate (1g in 10% glucose solution) infusion every day for 2 months as controls. RESULTS The total effective rates in TAD and control group were 80% and 63% respectively, with statistically significant difference(P<0.05). CONCLUSIONS TAD has excellent response rate in the treatment of patients with acute and chronic viral hepatitis.
关键词
谷胱甘肽
药物疗法
病毒性肝炎
glutathion/therapeutic use hepatitis, viral, human/drug therapy superinfection/drug therapy