血细胞分析仪检测肝病患者白细胞误差的研究

Studios of Leukocytes Error Using Hematology Analyzer in Patients with Liver Diseases

目的 现察血细胞分析仪检测重型肝炎患者WBC误差，探讨重型肝炎患者外周血病理因素对血细胞分析仪使用的影响。方法 分别采用血细胞分析仪（仪器法）和显微镜目视检测（手工法）对48例重型肝炎患者（肝病组）与50例健康人（健康组）进行WBC对比检测分析。结果 健康组仪器法与手工法WBC检测结果无显著差异（P〉0．05），肝病组仪器法与手工法WBC检测结果有极显著差异（P〈0．01）。结论 重型肝炎患者红细胞膜质类异常，影响血细胞分析仪WBC检测结果，应进行显微镜目视复查检测，以保证重型肝炎患者WBC检测结果的准确性。

Objective To observe the white blood cell（WBC）error usmg hematology analyzer in patients with severe hepatitis, and investigate the effects of pathological factors of peripheral blood on the using of hematology analyzer. Methods WBC count was measured in 48 patients with severe hepatitis（the liver disease group） and 50 healthy persons（the health group）by both hematology analyzer（the instrument method）and artificial microscopy （the manual method）separately. Results In the health group, the WBC count measured by the instrument method was no more than the count measured by the manual method（P〉0.05）. In the liver disease group, the WBC count measured by the instrument method was more than the count measured by the manual method（P〈0,01）. Conclusion This finding suggested the WBC count in severe hepatitis should be measured not only by hematology analyzer but also by artificial microscopy method in order to assure the accuracy of results.