期刊文献+

Impact of MELD score in predicting short-term survival after primary liver transplantation

Impact of MELD score in predicting short-term survival after primary liver transplantation
下载PDF
导出
摘要 Objective: To study the efficacy of model for end-stage fiver disease (MELD) in predicting short-term outcomes in patients undergoing liver transplantation (LT). Methods: The consecutive 62 patients who had received primary LT in our hospital from November 2000 to January 2005 were retrospectively analyzed. The pretransplantafion MELD and Child-Turcotte-Pugh (CTP) scores of these patients were calculated. Concordance c-statistic was used to assess the efficacies of MELD and CTP scores in predicting the first posttransplantation 3-month survival rate. Results: Among the 62 patients receiving primary LT, 12 died during the first 3-month period and the posttransplantation 3-month survival rate was 80.65%. The 3-month survival rate predicted by using CTP score and MELD score was 0.685 and 0.873, respectively. Unlike CTP calssificafion, MELD score indentified two subgroups of patients with CTP C with different overall survival (0.8824 vs 0.4545, ;X^2= 7.00, P = 0.0081 ). Conclusion: Our present study shows that MELD score could offer more accurate prediction for short-term survival in patients who undergo primary LT than CTP score. Objective: To study the efficacy of model for end-stage fiver disease (MELD) in predicting short-term outcomes in patients undergoing liver transplantation (LT). Methods: The consecutive 62 patients who had received primary LT in our hospital from November 2000 to January 2005 were retrospectively analyzed. The pretransplantafion MELD and Child-Turcotte-Pugh (CTP) scores of these patients were calculated. Concordance c-statistic was used to assess the efficacies of MELD and CTP scores in predicting the first posttransplantation 3-month survival rate. Results: Among the 62 patients receiving primary LT, 12 died during the first 3-month period and the posttransplantation 3-month survival rate was 80.65%. The 3-month survival rate predicted by using CTP score and MELD score was 0.685 and 0.873, respectively. Unlike CTP calssificafion, MELD score indentified two subgroups of patients with CTP C with different overall survival (0.8824 vs 0.4545, ;X^2= 7.00, P = 0.0081 ). Conclusion: Our present study shows that MELD score could offer more accurate prediction for short-term survival in patients who undergo primary LT than CTP score.
出处 《Journal of Nanjing Medical University》 2006年第2期116-119,共4页 南京医科大学学报(英文版)
关键词 MELD Child-Turcotte-Pugh Hver transplantation SURVIVAL MELD Child-Turcotte-Pugh Hver transplantation survival
  • 相关文献

参考文献10

  • 1DiamondGA.Futureimperfect:thelimitationsofclinicalprediction modelsandthelimitsofclinicalprediction[].Journal of the American College of Cardiology.1989
  • 2GibbonsRD,DuanN,MeltzerD.Inequitiesinlivertransplantallo cation[].Science.2000
  • 3BrownRSJr,KumarKS,RussoMW,etal.Modelforend stage liverdiseaseandChild Turcotte Pughscoreaspredictorsofpretrans plantationdiseaseseverity,posttransplantationoutcome,andresource utilizationinUnitedNetworkforOrganSharingstatus2Apatients[].Liver Transplantation.2002
  • 4HanleyJA,McNeilBJ.Amethodofcomparingtheareasunderre ceiveroperatingcharacteristiccurvesderivedfromthesamecases[].Radiology.1983
  • 5HanleyJA,McNeilBJ.Themeaninganduseoftheareaunderare ceiveroperatingcharacteristic(ROC)curve[].Radiology.1982
  • 6delOlmoJA,Flor LorenteB,Flor CiveraB,etal.Riskfactorsfor nonhepaticsurgeryinpatientswithcirrhosis[].World Journal of Surgery.2003
  • 7FormanLM,LuceyMR.Predictingtheprognosisofchronicliver disease:anevolutionfromChildtoMELD[].Hepatology.2001
  • 8KamathPS,WiesnerRH,MalinchocM,etal.Amodeltopredict survivalinpatientswithend stageliverdisease[].Hepatology.2001
  • 9D’AmicoG.DevelopingconceptsonMELD:deltaandcutoffs[].Journal of Hepatology.2005
  • 10SrikurejaW,KyuloNL,RunyonBA,etal.MELDscoreisabetter prognosticmodelthanCTPscoreorDiscriminantFunctionscorein patientswithalcoholichepatitis[].Journal of Hepatology.2005

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部