槲皮素对运动训练大鼠脑组织自由基代谢的影响

Effect of quercetin on exercise performance and free radical metabolism in brain tissue of trained rats

通过对运动训练大鼠在安静状态、非力竭运动状态及力竭运动状态下脑组织超氧化物歧化酶 (T-SOD)、铜锌超氧化物歧化酶(CuZn-SOD)、过氧化氢酶(CAT)和谷胱甘肽过氧化物酶(GSH-Px)活性及丙二醛 (MDA)含量的测定,研究了槲皮素对运动训练大鼠脑组织自由基代谢及运动能力的影响。结果表明,服用槲皮素的运动训练组大鼠力竭运动时间明显高于力竭对照组(P<0．05);服用槲皮素的运动训练组及运动力竭组大鼠脑组织T-SOD,CuZn-SOD,CAT和GSH-Px活性均高于其相应的对照组,MDA含量低于其相应的对照组(P< 0．05)。这表明槲皮素是一种有效的自由基清除剂,可减轻运动后因脂质过氧化而产生的自由基对机体的损伤,保护细胞膜的完整性,具有增强氧化酶活力和提高大鼠运动能力的作用。

The activities of T- SOD,CuZn-SOD,GSH Px and CAT as well as MDA content in rats brain tissue are measured respectivety in sedentary status,exercise training status and exhaustive exercise sta ti-oxidative,clearing the free radicals and modulating the body endocrine system. It can relieve some bad effects of the intensity endurance exercise on the body and promote the capability of exercise.