高压氧治疗介入时间对急性脑梗死疗效的影响

The influence of hyperbaric oxygen therapy started at different time on patients with acute cerebral infarction

目的探讨不同时机高压氧（HBO）治疗对急性脑梗死患者疗效的影响。方法60例急性脑梗死患者按开始进行HBO治疗的时间分为两组，即伤后48h至7d组（早期组）和伤后8～15d组（晚期组）各30例，对两组患者在HBO治疗前、治疗30d后分别进行神经功能缺损程度、简式Fugl—Meyer和改良Barthel指数评定，并进行两组之间的比较。结果HBO治疗30d后，早期组患者的神经功能缺损程度和运动功能改善较晚期组显著、两组间简式Fugl—Meyer和改良Barthe!指数评分比较，差异有统计学意义（P〈0．05）。结论高压氧治疗急性脑梗死疗效可靠，在伤后7d以内开始HBO治疗效果更好。

Objective To study the influence of different starting time of hyperbaric oxygen（HBO） therapy on severe brain injury patients. Methods 60 cases of acute cerebral infarction patients were divided into 2 groups, namel 48 hours to 7 days group（group A） and 8 days to 15 days group（group B） after injury. Fugl-Meyer assemment and modified Barthel index were employed to assess the patients before and after HBO for 30 days in the 2 groups. Results After 30 days of HBO therapy the Fug-Meyer assemment and modified Barthel index in the A group were better than those of B group, there were significant differences between the 2 groups（ P〈0.05）. Conclusion The influence of hyperbaric oxygen（HBO） therapy is reliable in acute cerebral infaction. And it is more effective within 7 days of onset of acute cerebral infaction.