低分子肝素治疗慢性肺心病40例临床分析

Effects of Lower-Molecular-Weight Heparin in Treatment of 72 cases of Chronic Pulmonary Heart Disease

目的观察低分子肝素治疗慢性肺心病对血液流变学、凝血功能及临床预后的影响。方法测定72例慢性肺心病患者的血液流变学及凝血指标。72例慢性肺心病患者随机分成治疗组和对照组,对照组给予常规治疗,治疗组在常规治疗基础上加低分子肝素治疗10天。结果慢性肺心病患者的血液流变学及凝血指标显著增高,低分子肝素钙治疗后血液流变学及凝血指标显著降低(P<0.01),提高了临床治愈率。结论老年肺心病患者血黏度增高,低分子肝素治疗可有效改善患者的临床预后。

Objective To study the effect of lower-molecular-weight heparin （LMWH） for the patients＇ hemorheology ,coagulation and prognostic with chronic pulmonary heart disease. Methods Measuring the hemorheology and coagulation data of 72 patients who suffered from chronic pulmonary heart disease. The patients were divided into two groups： the treatment group and control group. The patients in control group were given routine treatment and the others were given routine treatment plus LMWH for 10 days, Results The hemorheology and coagulation data of the patients with chronic pulmonary heart disease were high （P〈0.05）, and decreased significantly after treatment of LMWH, and the rate of cure improved. Conclusion Blood viscosity was higher in elder patients with chronic pulmonary heart disease, the treatment of LMWH would improve the prognostic,