卵巢癌等人体肿瘤细胞体外抗癌药物敏感试验

IN VITRO SENSITIVITY EXPERIMENT OF HUMAN TUMOR CELLS TO ANTICANCER DRUGS

本实验用~3H-TdR掺入法。对20例肿瘤患者的手术标本及胸水做了体外抗癌药物的敏感试验,临床按试验结果选用抗癌药物。其总符合率为80％,敏感指数为78％,耐药指致为82％,本试验可为临床化疗选药提供参考依据。

The anticancer drug sensitivity test were determined by 3H-TDR incorporation test from resected tumor specimens or pleura fluid in 20 patients with malignancies. The results showed the total correspondence rate with the clinic therapeutic results was 80% the sensitivity index and resistance index was 78 and 90% respectively. So this method was thought to be useful in chemotherapeutic agents selection in clinical practice.