摘要
用乌贼墨喂养小鼠后采集血清,经体外检测对L_(929)细胞的细胞毒作用表明:乌贼墨在动物体内具有明显的肿瘤坏死因子(TNF)诱生作用。并且此种血清对人类肿瘤(胃癌GM_(803);大肠癌Y_(93))细胞株也具有不同程度的杀伤作用。
TNF in sera from BALB/c mice treated with sepia was detected by L929 cell killing assay. Sera of the mice treated with saline were used as control. Results showed a significant TNF -inducing activity of sepia in animals. And the induced sera were also cytotoxic to human cancer cells,such as GM803 and Y99.
出处
《中国海洋药物》
CAS
CSCD
1996年第1期10-12,共3页
Chinese Journal of Marine Drugs
